- Basic information
- CohesinDB ID: CDBP00413360
- Locus: chr21-14916689-14917170
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Data sourse: GSE206145-GSE177045, GSE72082, GSE105028, GSE152721, GSE68388
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Cell type: MCF-7, HAP1, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 71%,
"7_Enh": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NCOA2, NANOG, SMC1A, PPARG, PGR, POU5F1, NKX2-2, RBBP5, SOX2, CHD8, FOXA2, GTF2B, SMAD3, FOXA1, HOXB13, ERG, RELA, CREBBP, RUNX2, MYC, GATA4, RAD21, CHD7, ARNT, PBX4, HIF1A, RXRA, NKX2-1, GATA3, STAT3, NRIP1, TERF2, MED1, CDX2, TLE3, KLF4, NR3C1, CEBPB, TEAD1, NR2F2, ELF1, CREB1, PIAS1, TCF7L2, TRIM28, ZNF217, TP53, HNF1B, ESR1, GRHL2, PHOX2B, ELF3, TCF12, RBM22, BAF155, EP300, SP1, HNF4A, AR, IRF1, TAF1, REST, GATA2, RXR, EGLN2, YAP1, ASH2L, BRD4, PHIP, FOXP1, TEAD4, NCOR2, AHR
- Target gene symbol (double-evidenced CRMs): NRIP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops