- Basic information
- CohesinDB ID: CDBP00413375
- Locus: chr21-14952341-14953601
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Data sourse: GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR501LQA, ENCSR000BLY, GSE121355, GSE103477, GSE25021, GSE108869, ENCSR000EDW, ENCSR917QNE, ENCSR000EFJ, GSE93080, ENCSR000DZP, GSE138405, GSE76893, GSE206145-NatGen2015, GSE120943, ENCSR703TNG, ENCSR000EEG, ENCSR338DUC, GSE98367, ENCSR000BLS, ENCSR000BMY, ENCSR000BTQ, ENCSR167MTG, GSE110061, ENCSR000HPG, GSE155324, ENCSR054FKH, GSE126990, GSE50893
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Cell type: MDM, GM2610, Liver, GM2630, Fibroblast, HeLa-S3, IMR-90, SNYDER, Monocytes, Lymphoblast, GM12878, GM12891, SK-N-SH, GM19239, Macrophage, MCF-7, Hela-Kyoto, HCT-116, Hep-G2, A-549
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 12% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.778
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 97%,
"5_TxWk": 3%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, ZBTB2, PAX8, SMC1A, TEAD1, RAD21, ESR1, OTX2, GATA3, SMC3, SRF, SMC1, FOXA1, PAX5, CTCF, TRIM22, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): HSPA13,SAMSN1,RBM11
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000185272,
ENSG00000155304,
ENSG00000155307,
- Related loop:
chr21:14225000-14250000~~chr21:14950000-14975000,
chr21:14275000-14300000~~chr21:14950000-14975000,
chr21:14375000-14400000~~chr21:14950000-14975000,
chr21:14475000-14500000~~chr21:14950000-14975000,
chr21:14650000-14675000~~chr21:14950000-14975000,
chr21:14775000-14800000~~chr21:14950000-14975000,
chr21:14850000-14875000~~chr21:14950000-14975000,
chr21:14863287-14865668~~chr21:14952411-14953711,
chr21:14950000-14975000~~chr21:15125000-15150000,
chr21:14950000-14975000~~chr21:15150000-15175000,
chr21:14950000-14975000~~chr21:15250000-15275000,
chr21:14950000-14975000~~chr21:15275000-15300000,
chr21:14950000-14975000~~chr21:15425000-15450000,
chr21:14950000-14975000~~chr21:15450000-15475000,
chr21:14950000-14975000~~chr21:15475000-15500000,
chr21:14950000-14975000~~chr21:15525000-15550000,
chr21:14950000-14975000~~chr21:15575000-15600000,
chr21:14950000-14975000~~chr21:16125000-16150000,