Browse_each

Basic information

CohesinDB ID: CDBP00413377

Locus: chr21-14955906-14957615

Data sourse: ENCSR000EFJ, GSE206145-GSE177045, GSE72082, GSE86191, ENCSR000HPG, GSE206145, GSE206145-NatGen2015, GSE68388, ENCSR703TNG, GSE25021, GSE94872, GSE165895

Cell type: MCF-7, RPE, Fibroblast, HCT-116, HUVEC, IMR-90, HuCC-T1, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 5% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.911

Subunit: SA1,Rad21,SMC1,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES,Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 64%, "7_Enh": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF283, PGR, PAF1, SIN3A, SMAD3, FOXA1, HOXB13, ERG, RELA, CREBBP, NEUROD1, RUNX2, RAD21, PRDM1, ARNT, PBX4, OTX2, GATA3, SMARCE1, FOXM1, MAX, NKX3-1, GATA1, AGO2, NRIP1, ZNF143, ARNTL, CEBPB, NR2F2, TRIM28, TEAD1, CREB1, PIAS1, TFAP2C, ZNF217, ESR1, GRHL2, RBM22, SPI1, BAF155, TFAP2A, EP300, AR, DPF2, HDAC2, GATA2, SSRP1, ASH2L, BRD4, PHIP, CTBP2, ZNF766, CUX1, STAG1, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): NRIP1,RBM11,SAMSN1,HSPA13

Function elements

Human SNPs: Gastroesophageal_reflux_disease

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000185272, ENSG00000155304, ENSG00000155307, ENSG00000180530,

eachgene

Deatailed information for cohesin site CDBP00413377