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Basic information

CohesinDB ID: CDBP00413379

Locus: chr21-14959237-14960295

Data sourse: ENCSR167MTG, GSE138405, ENCSR768DOX, GSE206145-NatGen2015, GSE138105

Cell type: Fibroblast, Hela-Kyoto, Hep-G2, SLK, A-549

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SA2,Mau2,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 59%, "5_TxWk": 36%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, ZNF660, SOX2, NME2, XBP1, FOXA1, HLF, SRSF4, CHD7, PRDM1, TEAD1, TRIM28, BCLAF1, SNAI2, ESR1, OCA2, JUN, CTCF, GATA6, SOX5, GATAD2A, TFAP2C, EED, CHD8, POU5F1, TOP2A, ZNF317, ZNF205, MLLT3, HOXC5, ERG, MYC, RAD21, GRHL3, RXRA, NKX2-1, PROX1, STAT3, IKZF1, NR3C1, CEBPB, EPAS1, EZH2, ZNF652, SPI1, IRF1, GATA2, FLI1, SMC1A, CEBPA, SOX13, ZNF534, SMAD3, RUNX2, GATA4, GR, ARNT, PBX4, DAXX, FOS, SUPT5H, MED1, PML, CEBPD, MYB, ZMYM3, SUPT16H, HIF2A, RBM22, BCL11A, TFAP2A, HNF4A, ZNF605, SRSF9, PHIP, SMC3, NCOR2, ZNF283, PPARG, FOXA2, PAF1, ZSCAN16, ZNF823, HOXB13, BCL3, RELA, JUNB, HIF1A, GATA3, MAX, GATA1, AGO2, ZNF143, KLF4, CEBPG, NCOA3, NR2F2, TCF7L2, AR, EGLN2, NOTCH3, BRD4, JUND, SCRT1, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): SAMSN1,HSPA13,NRIP1,RBM11

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000185272, ENSG00000155304, ENSG00000155307, ENSG00000180530,

eachgene

Deatailed information for cohesin site CDBP00413379