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Basic information

CohesinDB ID: CDBP00413385

Locus: chr21-14989089-14989683

Data sourse: GSE206145, ENCSR000BTU, GSE116344, ENCSR230ZWH

Cell type: RPE, Liver, Ishikawa, RH4

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 34%, "7_Enh": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, SOX2, MEIS2, XBP1, FOXA1, PBX2, ZFHX2, HDGF, MEN1, ATF3, CHD7, PRDM1, CBFB, SMARCE1, MITF, TRIM28, ETV1, SNAI2, ESR1, TP73, CTCF, JUN, BAF155, GATA6, TEAD4, PDX1, TFAP2C, EED, POU2F2, CHD8, NANOG, ZNF263, POU5F1, TOP2A, CTBP1, ZBTB48, DUX4, ZSCAN5A, NONO, SRF, ZNF205, ERG, MYC, SMARCA4, EOMES, HOMEZ, RAD21, ARID1B, GRHL3, RXRA, NKX2-1, GABPA, STAT3, NKX3-1, IKZF1, DACH1, VDR, ARNTL, ZNF750, NR3C1, CEBPB, KMT2A, CREB1, GRHL2, ZHX2, SPI1, HDAC2, GATA2, ZNF644, SIX2, FLI1, NCOA2, RUNX1, SMC1A, MAFG, CEBPA, NKX2-2, SIN3A, ZFX, SMAD3, TWIST1, CREBBP, IRF2, ZNF384, RUNX2, SMAD2, ARNT, PBX4, SOX11, ATF2, PRDM9, ZNF48, SMAD4, FOS, CDK8, SUPT5H, MED1, ZEB1, TEAD3, PIAS1, C11orf30, RBM22, MAFK, BCL11A, SP1, REST, ZNF479, ARID1A, ASH2L, PHIP, BCOR, FOXP1, ZNF316, FOXA2, PAF1, MIER2, ZSCAN16, WT1, MAFF, FOXF1, HOXB13, RELA, NEUROD1, ISL1, HIF1A, OTX2, GATA3, TAL1, MAX, NRIP1, ZNF143, AGO2, GATA1, HAND2, CEBPG, NCOA3, NEUROG2, PKNOX1, NFKB1, MYOD1, EGR2, PHOX2B, T, BRD2, AR, PAX3-FOXO1, EGLN2, ZBTB26, HSF1, NOTCH3, BRD4, SCRT1, JUND, CLOCK, ZNF440, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): USP25,NRIP1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 9

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000180530, ENSG00000155313,

eachgene

Deatailed information for cohesin site CDBP00413385