- Basic information
- CohesinDB ID: CDBP00413390
- Locus: chr21-15001026-15001397
-
Data sourse: ENCSR000EFJ, GSE206145-GSE177045, GSE165895
-
Cell type: MCF-7, IMR-90, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,Rad21,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
52% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 49%,
"7_Enh": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, PGR, ZNF660, ZSCAN5C, SOX2, NME2, HNF1A, XBP1, FOXA1, SUZ12, ZFHX2, HNRNPK, HDGF, MEN1, ZNF90, ATF3, NFIC, ZNF362, HNRNPUL1, RUNX3, PRDM1, CHD7, IKZF3, ZBTB44, ZNF189, PAX5, ZSCAN4, CDX2, ZNF467, MYOG, MAF, TEAD1, BCLAF1, TRIM28, KLF6, ETV1, ZNF217, ESR1, HNF1B, USF2, ZNF561, CTCF, TCF12, JUN, EP300, BAF155, GATA6, SOX4, PRDM4, IRF4, MED12, ZNF674, TEAD4, GATAD2A, PDX1, RBPJ, TFAP2C, POU2F2, NANOG, CHD8, POU5F1, BRD3, TOP2A, MYCN, SRC, CTBP1, ZNF317, ZBTB17, DUX4, ZSCAN21, ZBTB48, ERG2, HIC1, SP4, ERG, ZBTB21, HOXC5, USP7, ASCL1, OGG1, ONECUT1, MYC, EOMES, SMARCA4, HOMEZ, RAD21, LHX2, RXRA, BATF3, GABPA, STAT3, XRCC5, NKX3-1, LEF1, NR2F6, ZNF639, ARNTL, VDR, NR3C1, ESRRA, CEBPB, KMT2A, CREB1, EZH2, FEZF1, GRHL2, ZNF652, ZHX2, SPI1, MIXL1, ZNF664, IRF1, HDAC2, GATA2, ZNF644, SIX2, FLI1, MXI1, MRTFB, NCOA2, MYF5, RUNX1, CTNNB1, BCL6, NKX2-2, SIN3A, ZNF534, POU4F2, ZFX, SMAD3, ZFP37, ZNF770, ERG3, SMARCC1, PRDM10, CREBBP, ZNF384, RARA, NOTCH1, ZNF35, RUNX2, ZSCAN30, SMAD2, OSR2, CDK6, PBX4, ARNT, DAXX, SOX11, ATF2, SMAD4, ETV6, FOXM1, SUPT5H, FOS, CHD1, MED1, ZEB1, TERF1, TEAD3, MYB, SCRT2, PIAS1, SUPT16H, NCOA1, RBM22, USF1, MAFK, BCL11A, SP1, HNF4A, TFAP2A, NIPBL, REST, ARID1A, ZNF479, POU2F3, ATF7, CTBP2, PHIP, BCOR, GLIS2, FOXP1, SMC3, MLLT1, STAG1, STAG2, ZNF394, PAX7, TRP47, PPARG, FOXA2, CREM, PAF1, GTF2B, WT1, ESR2, FOXF1, ZNF574, ZBTB33, ZNF580, HOXB13, KDM1A, YY1, RELA, JUNB, NEUROD1, BRG1, ISL1, ZIC2, HIF1A, PCGF1, OTX2, GATA3, BATF, TAL1, MAX, NRIP1, GATA1, AGO2, ZNF143, HAND2, TLE3, KLF4, BCL11B, SP7, NCOA3, NR2F2, ZFP69B, NR2F1, TP53, PKNOX1, ZSCAN22, MYOD1, EGR2, PHOX2B, ELF3, BRD2, T, KAT8, TBX21, BHLHE40, AR, PAX3-FOXO1, TAF1, ZNF324, ZBTB42, ZNF366, ZNF280D, NOTCH3, BRD4, ZNF248, JUND, MAZ, ZNF440, TBX2, AHR
- Target gene symbol (double-evidenced CRMs): NRIP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000180530,
- Related loop:
chr21:14850000-14875000~~chr21:14975000-15000000,
chr21:14875000-14900000~~chr21:14975000-15000000,
chr21:14875000-14900000~~chr21:15000000-15025000,
chr21:14975000-15000000~~chr21:15150000-15175000,
chr21:14975000-15000000~~chr21:15175000-15200000,
chr21:14975000-15000000~~chr21:15450000-15475000,
chr21:14975000-15000000~~chr21:15725000-15750000,
chr21:14975000-15000000~~chr21:16175000-16200000,
chr21:14975000-15000000~~chr21:16550000-16575000,
chr21:14975000-15000000~~chr21:21700000-21725000,
chr21:14975000-15000000~~chr21:34500000-34525000,
chr21:15000000-15025000~~chr21:16275000-16300000,
chr21:15000000-15025000~~chr21:16550000-16575000,
chr21:15000000-15025000~~chr21:17600000-17625000,