- Basic information
- CohesinDB ID: CDBP00413397
- Locus: chr21-15022316-15023068
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Data sourse: GSE138405, GSE110061, GSE206145-NatGen2015, GSE126990, GSE165895
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Cell type: Hela-Kyoto, Fibroblast, HCT-116, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
52% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 49%,
"15_Quies": 39%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, BCL6, PPARG, EZH2phosphoT487, PAF1, ZNF317, SMAD3, FOXA1, FOXF1, SRF, HOXB13, SMARCC1, ZNF19, RELA, MYC, RUNX2, GATA4, GR, DAXX, ARNT, OTX2, GATA3, GATA1, AGO2, MITF, MED1, TLE3, NR3C1, CEBPB, TEAD3, TEAD1, ZNF121, KMT2A, PIAS1, ESR1, MYOD1, CTCF, RBM22, MAFK, SPI1, BAF155, MNT, AR, GATA2, FLI1, SREBF1, RAD51, BRD4, BCOR
- Target gene symbol (double-evidenced CRMs): NRIP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 15
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000180530,
- Related loop:
chr21:14075000-14100000~~chr21:15025000-15050000,
chr21:14850000-14875000~~chr21:15025000-15050000,
chr21:14875000-14900000~~chr21:15000000-15025000,
chr21:14875000-14900000~~chr21:15025000-15050000,
chr21:15000000-15025000~~chr21:16275000-16300000,
chr21:15000000-15025000~~chr21:16550000-16575000,
chr21:15000000-15025000~~chr21:17600000-17625000,
chr21:15025000-15050000~~chr21:15200000-15225000,
chr21:15025000-15050000~~chr21:15475000-15500000,
chr21:15025000-15050000~~chr21:17775000-17800000,