- Basic information
- CohesinDB ID: CDBP00413400
- Locus: chr21-15030830-15032347
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Data sourse: ENCSR338DUC, GSE206145-NatGen2015, GSE135093, ENCSR153HNT, GSE116344, GSE165895
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Cell type: Fibroblast, RH4, Hep-G2, IMR-90, K-562, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
52% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 49%,
"15_Quies": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, SMARCA2, ZNF660, XBP1, HNF1A, FOXA1, HLF, ATF3, ZBTB44, RUNX3, PRDM1, PAX5, MITF, BACH2, CDX2, SFPQ, JMJD1C, ELF1, TRIM28, BCLAF1, ETV1, SMAD5, LMO2, HNF1B, OCA2, USF2, CTCF, JUN, DPF2, FOXA3, PDX1, RBPJ, EED, POU2F2, DUX4, SRF, ERG, ONECUT1, MYC, GRHL3, RXRA, NKX2-1, NKX3-1, IKZF1, NFE2, CEBPB, KMT2A, CREB1, MRTFA, ZHX2, SPI1, GATA2, ZNF644, SIX2, FLI1, MRTFB, RUNX1, SMC1A, MAFG, CEBPA, NKX2-2, SMAD3, SMARCC1, RUNX2, OSR2, PBX4, ATF2, SUPT5H, FOS, CDK8, MED1, TEAD3, TERF1, CEBPD, MYB, SCRT2, SUPT16H, C11orf30, RBM22, MAFK, BCL11A, SP1, HNF4A, ATF7, PHIP, FOXP1, PRDM6, NCOR2, MLLT1, FOXA2, PAF1, ZSCAN16, GTF2B, WT1, CDK9, HOXB13, ZNF19, RELA, YY1, OTX2, TAL1, ZNF143, AGO2, GATA1, SP7, ELF3, BRD2, TBX21, AR, NCOR1, IKZF2, BRD4, SCRT1, JUND, ZNF24, ZNF316
- Target gene symbol (double-evidenced CRMs): NRIP1
- Function elements
- Human SNPs: HDL_cholesterol_levels
- Number of somatic mutations (coding): 144
- Number of somatic mutations (non-coding): 0
- Related genes and loops