- Basic information
- CohesinDB ID: CDBP00413411
- Locus: chr21-15069437-15070135
-
Data sourse: GSE116344, ENCSR198ZYJ, ENCSR404BPV
-
Cell type: Neurons-H1, RH4
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC3,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
52% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 88%,
"14_ReprPCWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: ZNF483, SKI, FOXA2, CEBPA, HMG20A, SOX13, MIER2, XBP1, DUX4, MAFF, FOXA1, TBX3, SAP130, GATAD1, ARID3A, RXRB, HNF4G, KDM1A, RARA, USP7, HOMEZ, ARNT, XRCC5, MIER3, KLF4, MYOG, NR3C1, TEAD3, TEAD1, CEBPB, KMT2A, NR2F2, CEBPG, LMO2, TP53, ZNF652, ELF3, KAT8, EP300, MIXL1, ARID4B, AR, SOX5, HNF4A, PAX8, REST, ASH2L, ZGPAT, PHIP, NFIL3, FOXA3, GATAD2A, ZNF316
- Target gene symbol (double-evidenced CRMs): NRIP1,SAMSN1,HSPA13,USP25
- Function elements
- Human SNPs: Left_ventricle_wall_thickness
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 17
- Related genes and loops
- Related gene:
ENSG00000155304,
ENSG00000155307,
ENSG00000180530,
ENSG00000155313,
- Related loop:
chr21:14253183-14254696~~chr21:15062247-15066667,
chr21:14259014-14260613~~chr21:15062794-15066469,
chr21:14375000-14400000~~chr21:15050000-15075000,
chr21:14375000-14400000~~chr21:15075000-15100000,
chr21:14400000-14425000~~chr21:15050000-15075000,
chr21:14525000-14550000~~chr21:15050000-15075000,
chr21:14850000-14875000~~chr21:15050000-15075000,
chr21:14862220-14865605~~chr21:15064456-15067091,
chr21:14862240-14865713~~chr21:15062575-15066369,
chr21:14862269-14865635~~chr21:15064553-15067078,
chr21:14862528-14865734~~chr21:15064383-15066714,
chr21:14863074-14865706~~chr21:15062524-15066377,
chr21:14863114-14865715~~chr21:15062247-15066667,
chr21:14863229-14865687~~chr21:15063337-15066739,
chr21:14866302-14867752~~chr21:15062794-15066469,
chr21:14875000-14900000~~chr21:15050000-15075000,
chr21:14878983-14881740~~chr21:15064456-15067091,
chr21:14900000-14925000~~chr21:15050000-15075000,
chr21:15050000-15075000~~chr21:15200000-15225000,
chr21:15050000-15075000~~chr21:15225000-15250000,
chr21:15050000-15075000~~chr21:15425000-15450000,
chr21:15050000-15075000~~chr21:15475000-15500000,
chr21:15050000-15075000~~chr21:15550000-15575000,
chr21:15050000-15075000~~chr21:15825000-15850000,
chr21:15061979-15064702~~chr21:15482166-15484539,
chr21:15062163-15066356~~chr21:15482418-15484253,
chr21:15062193-15066426~~chr21:15482133-15484587,
chr21:15062205-15066426~~chr21:15482183-15484335,
chr21:15062223-15066649~~chr21:15482380-15484257,
chr21:15062247-15066667~~chr21:15482157-15484375,
chr21:15062524-15066377~~chr21:15482195-15484456,
chr21:15062529-15066349~~chr21:15482321-15484221,
chr21:15062531-15066418~~chr21:15482135-15484281,
chr21:15062575-15066369~~chr21:15482132-15484427,
chr21:15062585-15066485~~chr21:15482230-15484353,
chr21:15062590-15066457~~chr21:15482560-15484272,
chr21:15062613-15066552~~chr21:15482262-15484309,
chr21:15062794-15066469~~chr21:15482537-15484345,
chr21:15064446-15065859~~chr21:15482105-15484266,
chr21:15064456-15067091~~chr21:15482170-15484279,
chr21:15064511-15066370~~chr21:15482164-15484373,
chr21:15064522-15065940~~chr21:15482543-15484384,
chr21:15064549-15066726~~chr21:15482189-15484221,
chr21:15065167-15066394~~chr21:15482181-15484302,
chr21:15075000-15100000~~chr21:15200000-15225000,
chr21:15075000-15100000~~chr21:15450000-15475000,