- Basic information
- CohesinDB ID: CDBP00413413
- Locus: chr21-15073893-15074094
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Data sourse: GSE206145, GSE120943, GSE98367
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Cell type: RPE, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
52% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 94%,
"14_ReprPCWk": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PRDM1, TAL1
- Target gene symbol (double-evidenced CRMs): USP25,HSPA13,SAMSN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 11
- Related genes and loops
- Related gene:
ENSG00000155304,
ENSG00000155307,
ENSG00000155313,
- Related loop:
chr21:14375000-14400000~~chr21:15050000-15075000,
chr21:14375000-14400000~~chr21:15075000-15100000,
chr21:14400000-14425000~~chr21:15050000-15075000,
chr21:14525000-14550000~~chr21:15050000-15075000,
chr21:14850000-14875000~~chr21:15050000-15075000,
chr21:14875000-14900000~~chr21:15050000-15075000,
chr21:14900000-14925000~~chr21:15050000-15075000,
chr21:15050000-15075000~~chr21:15200000-15225000,
chr21:15050000-15075000~~chr21:15225000-15250000,
chr21:15050000-15075000~~chr21:15425000-15450000,
chr21:15050000-15075000~~chr21:15475000-15500000,
chr21:15050000-15075000~~chr21:15550000-15575000,
chr21:15050000-15075000~~chr21:15825000-15850000,
chr21:15075000-15100000~~chr21:15200000-15225000,
chr21:15075000-15100000~~chr21:15450000-15475000,