- Basic information
- CohesinDB ID: CDBP00413416
- Locus: chr21-15080508-15081008
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Data sourse: GSE115248, ENCSR000BLY, GSE206145, ENCSR000EHX, GSE116344, GSE108869, ENCSR000ECS
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Cell type: RH4, HEK293T, Kelly, HeLa-S3, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
52% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 95%,
"7_Enh": 3%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF660, SOX2, XBP1, FOXA1, ATF3, ZNF362, PRDM1, ZNF189, ZNF629, TRIM28, KLF10, ESR1, EP300, BAF155, DPF2, TEAD4, FOXA3, PDX1, EED, POU2F2, CHD8, POU5F1, MYCN, TOP2A, ZSCAN21, ZBTB17, ZNF317, STAT1, HIC1, ERG, ZBTB21, MYC, TSHZ1, GRHL3, STAT3, RCOR1, ZNF639, CEBPB, KMT2A, CREB1, KLF8, FEZF1, EBF3, GATA2, SIX2, FLI1, SMC1A, ZBTB24, MAFG, ZFP37, TBX3, TWIST1, PRDM10, GATA4, OSR2, ZNF184, SP3, PBX4, ATF2, ZNF518A, CBFA2T3, MAFB, SP2, FOS, ZEB1, MYB, PIAS1, BCL11A, GLIS2, PRDM6, ZNF394, FOXA2, CHD2, ZNF692, MAFF, HOXB13, KDM1A, YY1, RELA, NEUROD1, ISL1, HIF1A, OTX2, GATA3, TAL1, MAX, GATA1, HAND2, TLE3, CEBPG, BCL11B, SP7, TCF7L2, PHOX2B, BRD2, AR, PAX3-FOXO1, ZNF366, ZBTB42, ZNF280D, HSF1, NOTCH3, JUND, BRD4, CLOCK, ZSCAN23, TBX2, AHR
- Target gene symbol (double-evidenced CRMs): HSPA13
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops