- Basic information
- CohesinDB ID: CDBP00413426
- Locus: chr21-15138403-15142164
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, ENCSR501LQA, ENCSR150EFU, GSE25021, ENCSR330ELC, ENCSR000EDW, ENCSR000BUC, ENCSR917QNE, ENCSR000BTU, GSE76893, GSE116344, ENCSR895JMI, ENCSR000EEG, ENCSR338DUC, ENCSR193NSH, ENCSR768DOX, ENCSR000BLS, ENCSR981FDC, ENCSR247LSH, ENCSR807WAC, ENCSR620NWG, ENCSR635OSG, ENCSR495WGO, ENCSR984DZW, ENCSR217ELF, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR335RKQ, ENCSR054FKH, ENCSR153HNT, GSE68388, GSE83726, ENCSR748MVX
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Cell type: MCF-7, H1-hESC, RH4, Hep-G2, Ishikawa, A-549, K-562, Liver, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 13% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
52% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 42%,
"7_Enh": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, PGR, HMG20A, HNF1A, FOXA1, HLF, RBFOX2, RXRB, PBX2, KDM3A, TFAP4, SIN3B, TSC22D4, BMI1, NFIC, THRB, ZFP64, HNRNPUL1, ATF3, CHD7, MXD4, SMARCE1, CDX2, ZNF467, MYOG, JMJD1C, TEAD1, TRIM28, ELF1, ETV1, SNAI2, KLF6, NFE2L2, LMO2, RCOR2, HNF1B, ESR1, ZNF217, KLF10, MLL, CTCF, TCF12, EP300, BAF155, L3MBTL4, MNT, SOX9, GATA6, SOX5, DPF2, DMAP1, RFX5, RFX3, TEAD4, FOXA3, ZNF175, ZNF92, GATAD2A, PDX1, RBPJ, MLX, GTF2F1, TFAP2C, CHD8, MYCN, POU5F1, RUNX1T1, HHEX, BRD3, MTA2, ZSCAN5A, SRF, GATAD1, SAP130, PPARGC1A, ARID3A, TBP, HNF4G, PAX6, ERG, ASCL1, ZNF341, ETS1, ONECUT1, MYC, SMARCC2, HOMEZ, RAD21, ARID1B, GRHL3, RXRA, PROX1, NKX2-1, MCRS1, GABPA, STAT3, XRCC5, ZNF614, NKX3-1, IKZF1, MIER3, RCOR1, NR2F6, DNMT3B, VDR, TCF25, NR3C1, CEBPB, ESRRA, HNRNPL, KMT2A, CREB1, CCAR2, EZH2, TBL1XR1, FEZF1, ZNF652, GABPB1, ZHX2, SPI1, MIXL1, TFE3, ZSCAN2, IRF1, HBP1, HDAC2, SSRP1, GATA2, ZNF644, GATAD2B, MXD3, SIX2, ZNF121, DRAP1, ZGPAT, MXI1, HCFC1, SMARCA5, NFIL3, NCOA2, ETV5, RUNX1, THAP11, CTNNB1, BCL6, SMC1A, CEBPA, NKX2-2, CBX1, SIN3A, ZFX, SOX13, FIP1L1, POU4F2, SMAD3, CBX8, TBX3, SP5, TRIM22, SMARCC1, PRDM10, MYBL2, RARA, ZNF384, NFYC, CREBBP, GATA4, ZNF48, MAFB, NR2C1, SMARCB1, HMGXB4, FOS, TGIF2, MED1, TEAD3, ZEB1, CEBPD, MYB, SCRT2, U2AF1, ZMYM3, ZNF3, NR1H2, NCOA1, MBD1, RBM22, MAFK, SP1, NIPBL, BCL11A, HNF4A, NR4A1, ARID2, IKZF5, ZBTB7A, REST, ARID1A, RBM25, ASH2L, PHIP, TCF3, FOXP1, SMC3, NCOR2, STAG1, MLLT1, ETV4, NFATC3, SKI, PPARG, FOXA2, CREM, CHD2, MIER2, MAFF, FOXF1, ZBTB33, TCF7, CDK9, ZNF580, ZKSCAN1, HOXB13, KDM1A, YY1, RELA, FOXO3, BCL3, NEUROD1, TCF4, HIF1A, OTX2, BHLHE22, GATA3, MAX, NRIP1, GATA1, KLF4, CEBPG, NCOA3, NR2F2, NR2F1, PKNOX1, RUVBL1, MYOD1, ELF3, PHF5A, KAT8, BRD2, TBX21, NFKBIZ, ARID4B, BHLHE40, AR, RXR, EGR1, ZBTB26, NCOR1, NOTCH3, BRD4, JUND, HSF1, CLOCK, CUX1, SCRT1, SMAD4.1D12, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): NRIP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 16
- Related genes and loops