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Basic information

CohesinDB ID: CDBP00413428

Locus: chr21-15149683-15150166

Data sourse: ENCSR054FKH, ENCSR230ZWH, GSE72082, ENCSR917QNE

Cell type: Liver, Hep-G2

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 52% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 92%, "14_ReprPCWk": 3%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PPARG, HMG20A, CEBPA, SOX13, FOXA1, RXRB, ARID3A, ZKSCAN1, HNF4G, KDM1A, RARA, ZNF384, HOMEZ, RAD21, GRHL3, ARNT, GATAD2A, RXRA, ZNF614, MAFB, NR2F6, CDX2, TEAD3, TEAD1, TRIM28, NR2F2, RCOR2, ESR1, SP1, BCL11A, MIXL1, HNF4A, EP300, ASH2L, NCOR1, ZGPAT, FOXA3, ATF1

Target gene symbol (double-evidenced CRMs): HSPA13,SAMSN1,NRIP1,RBM11

Function elements

Human SNPs: Waist-to-hip_ratio_adjusted_for_BMI

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000185272, ENSG00000155304, ENSG00000155307, ENSG00000180530,

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Deatailed information for cohesin site CDBP00413428