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Basic information

CohesinDB ID: CDBP00413430

Locus: chr21-15155413-15155883

Data sourse: ENCSR167MTG, ENCSR230ZWH, GSE72082, GSE98367, ENCSR879KXD, ENCSR000BLS, ENCSR054FKH, GSE120943

Cell type: Monocytes, Hep-G2, K-562, Liver, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 52% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 77%, "7_Enh": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, FOSL1, E2F7, NME2, XBP1, KDM4B, FOXA1, MITF, CDX2, TRIM28, ESR1, CTCF, TCF12, MNT, E2F6, TRIM24, SOX6, TEAD4, FOXA3, GATAD2A, EHMT2, POU2F2, CHD8, MTA2, DUX4, TBP, HNF4G, MYC, ARID1B, HOMEZ, RAD21, GRHL3, XRCC5, ZNF614, RCOR1, NUFIP1, NR2F6, VDR, CEBPB, ESRRA, CREB1, TFE3, HDAC2, GATA2, ZNF644, NR2C2, NFIL3, ETV5, THAP11, BCL6, CBX1, HDAC1, CEBPA, CRY1, SOX13, ZFX, RARA, RUNX2, GATA4, HMBOX1, SMAD4, CBFA2T3, NR2C1, TEAD3, L3MBTL2, BCL11A, GSPT2, HNF4A, CBFA2T2, CBX3, YY1, RELA, GATA3, MGA, TAL1, MAX, NRIP1, ZNF143, GATA1, NCOA3, NR2F2, NR2F1, EGR1, ZBTB26, NCOR1, RNF2, JUND, MAZ, ZNF24, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): RBM11,SAMSN1,NRIP1,HSPA13

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000185272, ENSG00000155304, ENSG00000155307, ENSG00000180530,

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Deatailed information for cohesin site CDBP00413430