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Basic information

CohesinDB ID: CDBP00413433

Locus: chr21-15164026-15164374

Data sourse: GSE206145, GSE206145-NatGen2015, GSE111913, GSE86191

Cell type: RPE, Fibroblast, HCT-116, RT-112

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 52% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 81%, "5_TxWk": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFATC3, RUNX1, POU2F2, CHD8, SMC1A, TOP2A, ZFX, NME2, FOXA1, HOXB13, ERG, RELA, RUNX2, ARNT, HIF1A, TLE3, NCOA3, TEAD3, TRIM28, TEAD1, CREB1, PIAS1, ESR1, CTCF, SPI1, BAF155, AR, GATA2, ARID1A, HSF1, TEAD4, TFAP2C

Target gene symbol (double-evidenced CRMs): HSPA13,SAMSN1,NRIP1,RBM11

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene: ENSG00000185272, ENSG00000155304, ENSG00000155307, ENSG00000180530,

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Deatailed information for cohesin site CDBP00413433