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Basic information

CohesinDB ID: CDBP00413434

Locus: chr21-15164670-15165346

Data sourse: ENCSR167MTG, GSE72082, ENCSR501LQA, ENCSR676MJK, GSE76893, ENCSR000BLS, GSE206145, ENCSR335RKQ, ENCSR054FKH, ENCSR000EDE, GSE68388, ENCSR703TNG, GSE108869, ENCSR000ECS, ENCSR217ELF

Cell type: MCF-7, Hep-G2, HEK293T, A-549, HeLa-S3, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: NIPBL,SA1,Rad21,SMC1,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 52% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 79%, "7_Enh": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, FOSL1, PGR, HMG20A, FOXA1, RXRB, KDM3A, ATF3, THRB, ZFP64, MXD4, TP63, CDX2, TEAD1, TRIM28, KLF6, SNAI2, RCOR2, ZNF217, ESR1, OCA2, JUN, EP300, BAF155, SOX5, TRIM24, FOXA3, ZNF175, GATAD2A, GTF2F1, RBPJ, TFAP2C, MLX, BRD3, TOP2A, CTBP1, STAT1, PPARGC1A, SAP130, GATAD1, HNF4G, ERG, HOXC5, MYC, HOMEZ, RAD21, RXRA, NKX2-1, GABPA, STAT3, MIER3, TERF2, NR2F6, RCOR1, VDR, ESRRA, CEBPB, CREB1, TBL1XR1, GRHL2, ZNF652, GABPB1, SPI1, MIXL1, EHF, TFE3, HDAC2, GATA2, ZNF644, DRAP1, ZGPAT, NFIL3, NCOA2, ETV5, THAP11, BCL6, SMC1A, CEBPA, SOX13, SMAD3, SP5, SMARCC1, MYBL2, RARA, CREBBP, PBX4, DAXX, ZNF48, SMAD4, FOXM1, NR2C1, FOS, HMGXB4, CDK8, MED1, TEAD3, ZEB1, NR1H2, SP1, HNF4A, NKX2-5, IKZF5, REST, POU2F3, ASH2L, FOXP1, SMC3, SKI, PPARG, FOXA2, CREM, CHD2, MIER2, KDM1A, RELA, JUNB, TCF4, HIF1A, GATA3, MAX, NRIP1, GATA1, CEBPG, KLF4, NR2F2, NR2F1, TP53, ZNF334, NFKB1, MYOD1, ELF3, PHF5A, KAT8, NFKBIZ, AR, ARID4B, RXR, ZBTB26, BRD4, JUND, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): HSPA13,RBM11,SAMSN1,NRIP1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000185272, ENSG00000155304, ENSG00000155307, ENSG00000180530,

Tools:

Assay

refGene

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Cohesin site CDBP00413434

CDBP00413434 regulated genes

Related cohesin loop

Deatailed information for cohesin site CDBP00413434

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