- Basic information
- CohesinDB ID: CDBP00413439
- Locus: chr21-15183865-15184356
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Data sourse: GSE101921, GSE116344, GSE85526, ENCSR404BPV
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Cell type: Neurons-H1, HMEC, RH4, HEKn
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SMC3,Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
52% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 88%,
"7_Enh": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBFA2T2, SMC1A, CHD8, HDAC1, FOXA2, MEIS1, TOP2A, MEIS2, PBX2, KDM1A, RELA, JUNB, MYC, GATA4, ARID1B, ISL1, HIF1A, GATA3, TAL1, CBFA2T3, TP63, STAT3, GATA1, FOS, RCOR1, HAND2, MED1, KLF4, MAF, GFI1B, TRIM28, CREB1, EZH2, ESR1, TP53, TP73, TBX5, MYOD1, BRD2, JUN, EP300, EHF, AR, IRF1, NKX2-5, GATA2, HDAC2, ZSCAN29, TEAD4, STAG2
- Target gene symbol (double-evidenced CRMs): NRIP1
- Function elements
- Human SNPs: Systolic_blood_pressure
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops