- Basic information
- CohesinDB ID: CDBP00413441
- Locus: chr21-15191959-15193168
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Data sourse: GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR501LQA, ENCSR760NPX, ENCSR150EFU, ENCSR000ECS, GSE25021, ENCSR330ELC, GSE108869, ENCSR000BTU, GSE86191, GSE138405, GSE101921, ENCSR806UKK, ENCSR703TNG, ENCSR199XBQ, ENCSR895JMI, ENCSR193NSH, ENCSR768DOX, ENCSR981FDC, ENCSR247LSH, ENCSR807WAC, ENCSR620NWG, ENCSR767DFK, ENCSR495WGO, ENCSR984DZW, ENCSR217ELF, ENCSR000BTQ, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR676MJK, ENCSR335RKQ, ENCSR537EFT, ENCSR000EDE, GSE68388, GSE126990, ENCSR748MVX
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Cell type: MCF-7, HMEC, Hela-Kyoto, HCT-116, MCF-10A, Ishikawa, A-549, HeLa-S3, Liver, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 19% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
52% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 85%,
"7_Enh": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, ZNF660, MEIS2, FOXA1, HNRNPK, MEN1, BMI1, NFIC, WDHD1, ZNF444, SMARCE1, TP63, CDX2, MAF, TEAD1, ELF1, ZNF217, ESR1, USF2, JUN, TCF12, BAF155, EP300, MNT, DPF2, TRIM24, RFX5, NR5A2, SMC1, TEAD4, GTF2F1, PDX1, TFAP2C, GATAD2A, NANOG, CTBP1, ZBTB48, STAT1, TBP, HOXC5, ERG, MYC, RAD21, RXRA, GABPA, STAT3, NKX3-1, RCOR1, VDR, ZNF750, CEBPB, ESRRA, NR3C1, CREB1, GRHL2, TRPS1, EHF, ZSCAN2, HDAC2, GATA2, GATAD2B, SIX2, FLI1, HCFC1, SMARCA5, NCOA2, RUNX1, CBX1, SMC1A, CEBPA, SIN3A, AFF4, SMAD3, TRIM22, SMARCC1, CREBBP, ZNF384, ZXDC, GR, PBX4, NFIB, ELK1, DAXX, ARNT, FOXM1, FOS, CDK8, MED1, PIAS1, NR1H2, SP1, HNF4A, REST, ARID1A, ASH2L, CTBP2, MBD2, FOXP1, SMC3, ELL2, PPARG, FOXA2, CHD2, MAFF, ZNF823, HOXB13, KDM1A, RELA, NEUROD1, JUNB, BRG1, HIF1A, GATA3, MAX, NRIP1, MTA1, TLE3, KLF4, CEBPG, NCOA3, NR2F2, TCF7L2, KDM5B, TP53, PKNOX1, ZBTB6, NFKB1, PHOX2B, ELF3, AR, ZNF579, HSF1, BRD4, JUND, CLOCK, CUX1, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): NRIP1
- Function elements
- Human SNPs: Breast_cancer
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 13
- Related genes and loops