- Basic information
- CohesinDB ID: CDBP00413442
- Locus: chr21-15195617-15196347
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Data sourse: ENCSR167MTG, ENCSR000EEG, ENCSR338DUC, ENCSR230ZWH, GSE72082, GSE76893, ENCSR000BLS, ENCSR054FKH, GSE25021, ENCSR000EDW, ENCSR917QNE
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Cell type: Liver, Hep-G2
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
52% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 82%,
"7_Enh": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, PGR, HMG20A, FOXA1, RBFOX2, RXRB, KDM3A, TFAP4, ATF3, THRB, NFIC, MXD4, CDX2, TEAD1, KLF6, KLF10, RCOR2, ESR1, LMO2, EP300, SOX5, PAX8, TEAD4, FOXA3, ZNF175, GATAD2A, MLX, RBPJ, TOP2A, ZNF317, GATAD1, SAP130, ARID3A, HNF4G, ETS1, HOMEZ, RAD21, GRHL3, RXRA, MCRS1, ZNF614, XRCC5, MIER3, NR2F6, CEBPB, CREB1, TBL1XR1, ZNF652, MIXL1, TFE3, HDAC2, ZNF644, SIX2, DRAP1, ZGPAT, NFIL3, ETV5, THAP11, BCL6, SMC1A, CEBPA, SOX13, SP5, SMARCC1, MYBL2, RARA, ZNF48, SMAD4, HMGXB4, MED1, TEAD3, CEBPD, C11orf30, MAFK, SP1, HNF4A, IKZF5, REST, ASH2L, FOXP1, STAG1, SKI, PPARG, FOXA2, CREM, MIER2, MAFF, ZBTB33, TCF7, ZNF580, FOXO3, KDM1A, YY1, TAL1, MAX, CEBPG, NR2F2, ZNF334, ELF3, PHF5A, KAT8, ARID4B, NFKBIZ, ZBTB40, ZBTB26, NCOR1, JUND, ZNF24, DMAP1
- Target gene symbol (double-evidenced CRMs): NRIP1
- Function elements
- Human SNPs: Creatinine_levels
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000180530,
- Related loop:
chr21:14850000-14875000~~chr21:15200000-15225000,
chr21:14875000-14900000~~chr21:15200000-15225000,
chr21:14975000-15000000~~chr21:15175000-15200000,
chr21:15025000-15050000~~chr21:15200000-15225000,
chr21:15050000-15075000~~chr21:15200000-15225000,
chr21:15075000-15100000~~chr21:15200000-15225000,
chr21:15200000-15225000~~chr21:15425000-15450000,
chr21:15200000-15225000~~chr21:15450000-15475000,
chr21:15200000-15225000~~chr21:15475000-15500000,