- Basic information
- CohesinDB ID: CDBP00413444
- Locus: chr21-15202126-15202457
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Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE111913, GSE206145-NatGen2015
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Cell type: MCF-7, Fibroblast, HCT-116, RT-112, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
52% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 81%,
"5_TxWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZBTB48, OGG1
- Target gene symbol (double-evidenced CRMs): NRIP1
- Function elements
- Human SNPs: Breast_cancer
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000180530,
- Related loop:
chr21:14850000-14875000~~chr21:15200000-15225000,
chr21:14875000-14900000~~chr21:15200000-15225000,
chr21:14975000-15000000~~chr21:15175000-15200000,
chr21:15025000-15050000~~chr21:15200000-15225000,
chr21:15050000-15075000~~chr21:15200000-15225000,
chr21:15075000-15100000~~chr21:15200000-15225000,
chr21:15158984-15160931~~chr21:15205692-15207786,
chr21:15200000-15225000~~chr21:15425000-15450000,
chr21:15200000-15225000~~chr21:15450000-15475000,
chr21:15200000-15225000~~chr21:15475000-15500000,