Deatailed information for cohesin site CDBP00413445

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  • Basic information
  • CohesinDB ID: CDBP00413445
  • Locus: chr21-15202662-15205478
  • Data sourse: ENCSR000BTQ, ENCSR000BTU, ENCSR167MTG, GSE206145-GSE177045, GSE72082, GSE138405, GSE25021, GSE206145, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE130135, ENCSR703TNG, GSE126990, ENCSR000ECS
  • Cell type: MCF-7, Hela-Kyoto, Hep-G2, HEK293T, Ishikawa, HeLa-S3, K-562
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 10% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.911
  • Subunit: NIPBL,SA1,Rad21,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 52% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "15_Quies": 56%, "7_Enh": 18%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: MBD3, PGR, HMG20A, ZNF660, XBP1, FOXA1, RXRB, ZNF596, MEN1, THRB, NFIC, ZBTB44, PRDM1, ZNF189, ZNF736, ZNF467, TEAD1, TRIM28, ZNF121, SNAI2, ZNF217, ESR1, RCOR2, CTCF, TCF12, BAF155, EP300, SOX9, GATA6, SOX5, PRDM4, TEAD4, FOXA3, GATAD2A, TFAP2C, GLIS1, POU2F2, CHD8, MYCN, BRD3, ID3, CTBP1, ZNF317, ZBTB48, DUX4, STAT1, MLLT3, GATAD1, SRF, HIC1, TBP, ERG, ZNF626, ONECUT1, MYC, ARID1B, HOMEZ, RAD21, STAT3, NKX3-1, RCOR1, NR2F6, NR3C1, ESRRA, ZNF750, CEBPB, CREB1, EZH2, FEZF1, GRHL2, ZNF652, TRPS1, SPI1, ZNF664, HDAC2, GATA2, ZNF644, SIX2, FLI1, NFIL3, MRTFB, NCOA2, ATF1, RUNX1, THAP11, BCL6, SMC1A, CEBPA, SOX13, ZNF335, ZFX, ZFP37, SMARCC1, PRDM10, TWIST1, ZXDC, RARA, CREBBP, ZNF35, ZSCAN30, GATA4, OSR2, ARNT, NFIB, ATF2, ZNF48, SMAD4, HMBOX1, FOXM1, FOS, CDK8, MED1, TEAD3, ZEB1, PIAS1, NCOA1, TBX5, EVI1, NIPBL, NKX2-5, ZHX1, ATF7, ASH2L, CTBP2, PHIP, MBD2, FOXP1, PRDM6, SMC3, STAG1, CXXC4, ZNF394, PPARG, FOXA2, ZNF692, TCF7, HOXB13, RELA, ISL1, HIF1A, GATA3, MAX, ZNF613, NRIP1, GATA1, HAND2, TLE3, BCL11B, SP7, NCOA3, NR2F2, BAP1, NR2F1, ZNF687, TP53, PKNOX1, ZBTB6, PHOX2B, BRD2, KAT8, ARRB1, AR, ZNF366, BRD4, JUND, CUX1, MAZ, ZNF440, AHR
  • Target gene symbol (double-evidenced CRMs): NRIP1
  • Function elements
  • Human SNPs: Estimated_glomerular_filtration_rate
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 17
  • Related genes and loops
  • Related gene: ENSG00000180530,
  • Related loop: chr21:14850000-14875000~~chr21:15200000-15225000, chr21:14875000-14900000~~chr21:15200000-15225000, chr21:14975000-15000000~~chr21:15175000-15200000, chr21:15025000-15050000~~chr21:15200000-15225000, chr21:15050000-15075000~~chr21:15200000-15225000, chr21:15075000-15100000~~chr21:15200000-15225000, chr21:15139394-15141732~~chr21:15209659-15212431, chr21:15158984-15160931~~chr21:15205692-15207786, chr21:15200000-15225000~~chr21:15425000-15450000, chr21:15200000-15225000~~chr21:15450000-15475000, chr21:15200000-15225000~~chr21:15475000-15500000,
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