Deatailed information for cohesin site CDBP00413446

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  • Basic information
  • CohesinDB ID: CDBP00413446
  • Locus: chr21-15206151-15213136
  • Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR501LQA, ENCSR760NPX, ENCSR150EFU, GSE105028, GSE103477, GSE111537, GSE25021, ENCSR330ELC, ENCSR000EDW, GSE108869, ENCSR000BUC, ENCSR917QNE, GSE115602, ENCSR000BTU, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE101921, ENCSR806UKK, GSE120943, GSE112028, ENCSR199XBQ, ENCSR703TNG, GSE106870, GSE116344, ENCSR895JMI, ENCSR000EEG, ENCSR338DUC, GSE98367, ENCSR193NSH, ENCSR768DOX, ENCSR000BLS, GSE206145, GSE85526, ENCSR000ECE, ENCSR247LSH, ENCSR000BMY, ENCSR620NWG, ENCSR635OSG, ENCSR748MVX, ENCSR767DFK, ENCSR807WAC, ENCSR495WGO, ENCSR981FDC, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR000BTQ, GSE105004, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, GSE55407, ENCSR944ZCT, ENCSR676MJK, GSE111913, ENCSR335RKQ, ENCSR054FKH, ENCSR537EFT, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS, ENCSR481YWD
  • Cell type: MDM, RH4, CVB-hiPSC, GM19240, CVI-hiPSC, Liver, HuCC-T1, H9-hESC, RPE, HMEC, HEKn, Ishikawa, HeLa-S3, K-562, H1-hESC, SNYDER, Monocytes, GM12878, GM12891, GM2588, RT-112, HeLa-Tet-On, THP-1, Macrophage, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, MCF-10A, HEK293T, Hep-G2, A-549, HeLa, OCI-AML-3, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 42% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.600
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 52% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 45%, "7_Enh": 29%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, FOXA1, HLF, RXRB, KDM3A, ZBTB7B, HDGF, MEN1, TEAD1, SOX5, DEK, NR5A2, RFX3, KMT2B, GATAD2A, POU5F1, BRD3, HHEX, CTBP1, DUX4, STAT1, SAP130, ERG, SMARCA4, FOXK2, UBN1, RCOR1, NR2F6, CEBPB, CREB1, GABPB1, ZHX2, MIXL1, GATA2, ZNF644, MXD3, FLI1, DRAP1, MXI1, HCFC1, NR2C2, RUNX1, CEBPA, TBX3, SP5, SMARCC1, PRDM10, ZBTB2, ZXDC, ATF2, FOXM1, SMARCB1, PML, NR1H2, C11orf30, MBD1, STAT5A, GSPT2, IKZF5, ARID2, RBM25, MBD2, ELL2, ETV4, MEF2B, ZNF207, CREM, CHD2, NFATC1, WT1, MEF2C, JUNB, NEUROD1, BATF, KLF4, ELF3, ARID4B, RXR, EGLN2, ZBTB26, NR1H3, ADNP, ZNF316, FOSL1, ZNF660, HNF1A, TSC22D4, THRB, ATF3, ZFP64, RUNX3, WDHD1, TP63, JMJD1C, ELF1, KLF10, JUN, CTCF, L3MBTL4, MNT, DPF2, IRF4, MED12, RBPJ, TFAP2C, MLX, MTA2, ZBTB48, UTX, SRF, NONO, PBX1, HOMEZ, FOXP2, RXRA, BATF3, MIER3, HNRNPH1, VDR, NR3C1, ESRRA, KMT2A, CCAR2, TBL1XR1, GRHL2, KDM5A, SSRP1, NFIL3, THAP11, SOX13, AFF4, NFIB, ARNT, DAXX, BACH1, ZNF48, HMBOX1, ETV6, HMGXB4, TEAD3, USF1, BCL11A, SP1, TFAP2A, ATF7, ASH2L, CTBP2, SMC3, MLLT1, STAG1, STAG2, MTA3, MAFF, ZNF580, ZKSCAN1, BCL3, KDM1A, ISL1, GATA3, NRIP1, ZNF143, MTA1, TP53, NFKB1, PHOX2B, PHF5A, BRD2, KAT8, EGR1, RNF2, BRD4, JUND, CUX1, SMAD4.1D12, TBX2, CBX5, PGR, TFAP4, BMI1, ZNF444, MXD4, SMARCE1, KLF6, NFE2L2, ZNF217, ESR1, SOX9, TRIM24, RFX5, GTF2F1, POU2F2, ZSCAN5D, KDM4C, ZSCAN5A, TBP, HNF4G, HOXC5, ETS1, MYC, ARID1B, ZNF24, NKX2-1, GABPA, MCRS1, STAT3, IKZF1, INO80, DNMT3B, EZH2, ZNF652, SPI1, ZNF786, HDAC2, GATAD2B, NCOA2, ETV5, AHRR, BCL6, SIN3A, MEF2A, MYBL2, RARA, CREBBP, NR0B1, NFYC, SMAD4, CDK8, ZEB1, ZMYM3, NCOA1, RBM22, MAFK, HNF4A, REST, ARID1A, ZHX1, BCOR, FOXP1, PPARG, TBL1X, TCF7, FOXO3, RELA, TARDBP, MAX, ZNF592, NR2F1, TCF7L2, KDM5B, AR, YAP1, DMAP1, AHR, MBD3, FOSL2, HMG20A, RBFOX2, NFIC, KLF5, TRIM28, BCLAF1, ETV1, RCOR2, HNF1B, USF2, TCF12, EP300, BAF155, RAD51, E2F1, SMC1, TEAD4, FOXA3, ZNF175, EED, CHD8, MYCN, GATAD1, ARID3A, RAD21, XRCC5, ZNF614, NFE2, TCF25, ZNF750, TRPS1, HBP1, TFE3, EHF, IRF1, ZSCAN2, SREBF1, ZGPAT, SMC1A, CBX1, MAFG, ZFX, ZNF534, SMAD3, CBX8, TWIST1, PRPF4, RUNX2, CDK6, GATA4, GR, PBX4, NRF1, NR2C1, FOS, CHD1, TGIF2, MED1, CEBPD, MYB, ZNF3, NIPBL, ZBTB7A, PHIP, TCF3, SKI, FOXA2, MIER2, ZBTB33, CDK9, HOXB13, YY1, SP140, HIF1A, HAND2, TLE3, CEBPG, NCOA3, NR2F2, ZNF687, BHLHE40, NFKBIZ, TAF1, ZNF579, NOTCH3, CLOCK, MAZ, BRCA1
  • Target gene symbol (double-evidenced CRMs): NRIP1
  • Function elements
  • Human SNPs: Red_blood_cell_count
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 42
  • Related genes and loops
  • Related gene: ENSG00000180530,
  • Related loop: chr21:14850000-14875000~~chr21:15200000-15225000, chr21:14875000-14900000~~chr21:15200000-15225000, chr21:15025000-15050000~~chr21:15200000-15225000, chr21:15050000-15075000~~chr21:15200000-15225000, chr21:15075000-15100000~~chr21:15200000-15225000, chr21:15139394-15141732~~chr21:15209659-15212431, chr21:15158984-15160931~~chr21:15205692-15207786, chr21:15200000-15225000~~chr21:15425000-15450000, chr21:15200000-15225000~~chr21:15450000-15475000, chr21:15200000-15225000~~chr21:15475000-15500000,
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