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Basic information

CohesinDB ID: CDBP00413460

Locus: chr21-15272182-15272431

Data sourse: GSE67783, GSE72082, GSE111913, GSE68388, ENCSR703TNG, GSE25021

Cell type: MCF-7, RT-112, HSPC, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 88%, "7_Enh": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXA2, MEIS1, SMAD3, FOXA1, RELA, CREBBP, NFIC, ARNT, HIF1A, PBX4, NRF1, NKX2-1, GATA3, STAT3, FOXM1, MAX, NRIP1, GATA1, CEBPB, NCOA3, NR2F2, TEAD1, KDM5B, ESR1, TP53, GRHL2, EP300, SP1, AR, HDAC2, YAP1, BRD4, JUND, TEAD4, FOSL2

Target gene symbol (double-evidenced CRMs): NRIP1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000180530,

eachgene

Deatailed information for cohesin site CDBP00413460