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Basic information

CohesinDB ID: CDBP00413465

Locus: chr21-15291573-15292301

Data sourse: ENCSR000BLD, ENCSR000BTQ, ENCSR000BTU, ENCSR000EEG, ENCSR167MTG, GSE72082, GSE206145-GSE177045, GSE76893, ENCSR000BLS, GSE105028, ENCSR054FKH, ENCSR703TNG, GSE25021, GSE116344, ENCSR000EDW, GSE97394

Cell type: MCF-7, H1-hESC, RH4, Hep-G2, Ishikawa, H9-hESC, HUES64

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 7% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.922

Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 63%, "7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: THAP11, SMC1A, PPARG, CEBPA, POU5F1, HMG20A, RBPJ, SOX13, ZFX, MIER2, BCL6, GTF2B, SMAD3, FOXA1, GATAD1, SAP130, RXRB, HNF4G, KDM1A, TFAP4, CREBBP, RARA, ASCL1, ZBTB2, THRB, RUNX2, HOMEZ, RAD21, PBX4, GRHL3, HIF1A, ZNF48, SMAD4, STAT3, XRCC5, TP63, MAX, NR2F6, ZNF750, CEBPB, CEBPG, TEAD3, TEAD1, CEBPD, TCF7L2, SNAI2, KDM5B, RCOR2, ESR1, CHD8, GRHL2, CTCF, NIPBL, SPI1, TFAP2A, HNF4A, AR, SOX5, MIXL1, EP300, ARID4B, HDAC2, ZNF644, ELL2, ASH2L, ZGPAT, BRD4, NFIL3, SMC3, FOXA3, GATAD2A, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): NRIP1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000180530,

eachgene

Deatailed information for cohesin site CDBP00413465