- Basic information
- CohesinDB ID: CDBP00413466
- Locus: chr21-15292906-15293919
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, ENCSR150EFU, ENCSR000ECS, GSE25021, ENCSR330ELC, GSE108869, ENCSR000BUC, ENCSR917QNE, GSE115602, ENCSR000BTU, GSE165895, GSE138405, GSE76893, GSE101921, GSE138105, GSE130135, ENCSR703TNG, ENCSR199XBQ, GSE116344, ENCSR193NSH, GSE85526, ENCSR247LSH, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, ENCSR495WGO, ENCSR217ELF, ENCSR000BTQ, ENCSR853VWZ, ENCSR000EDE, GSE68388, GSE126990, ENCSR748MVX
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Cell type: MCF-7, H1-hESC, HMEC, Hela-Kyoto, RH4, HEKn, HEK293T, Hep-G2, SLK, Ishikawa, A-549, HeLa-S3, Liver, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 14% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.833
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 61%,
"7_Enh": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, HMG20A, ZNF660, SOX2, FOXA1, PBX2, TFAP4, ATF3, CHD7, PRDM1, WDHD1, SMARCE1, TP63, CDX2, KLF5, TEAD1, TRIM28, ELF1, KLF6, LMO2, ZNF217, HNF1B, TP73, ESR1, JUN, TCF12, CTCF, BAF155, EP300, MNT, GATA6, DPF2, SOX4, RFX5, DEK, TEAD4, GATAD2A, PDX1, TFAP2C, NANOG, CHD8, MYCN, POU5F1, CTBP1, SRF, HIC1, HOXC5, ERG, MYC, SMARCA4, ARID1B, RAD21, RXRA, NKX2-1, GABPA, STAT3, UBN1, IKZF1, RCOR1, ZNF750, ESRRA, NR3C1, CEBPB, CREB1, KLF8, GRHL2, TRPS1, ZHX2, IRF1, HDAC2, GATA2, FLI1, SMARCA5, MRTFB, SMC1A, CBX1, SIN3A, SOX13, SMAD3, ZFP37, SMARCC1, PRDM10, ZXDC, CREBBP, RARA, ZNF35, RUNX2, GATA4, OSR2, PBX4, ARNT, ATF2, FOXM1, PBX3, FOS, MED1, TEAD3, ZEB1, PIAS1, SETDB1, SP1, REST, ZHX1, ATF7, CTBP2, PHIP, MBD2, FOXP1, BCOR, SMC3, ELL2, STAG1, STAG2, FOXA2, MEIS1, HOXB13, KDM1A, RELA, JUNB, NEUROD1, HIF1A, GATA3, TAL1, MAX, NRIP1, ZNF143, HAND2, KLF4, BCL11B, SP7, NCOA3, NR2F2, KDM5B, ZNF687, TP53, MYOD1, ELF3, BRD2, AR, ZBTB40, YAP1, EGLN2, ZNF280D, RNF2, BRD4, ILF3, JUND, CUX1, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): NRIP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000180530,
- Related loop:
chr21:14850000-14875000~~chr21:15275000-15300000,
chr21:14866344-14867733~~chr21:15291005-15294045,
chr21:14875000-14900000~~chr21:15275000-15300000,
chr21:14950000-14975000~~chr21:15275000-15300000,
chr21:15150000-15175000~~chr21:15275000-15300000,
chr21:15275000-15300000~~chr21:15375000-15400000,
chr21:15275000-15300000~~chr21:15400000-15425000,
chr21:15275000-15300000~~chr21:15425000-15450000,
chr21:15275000-15300000~~chr21:15450000-15475000,
chr21:15275000-15300000~~chr21:15475000-15500000,