- Basic information
- CohesinDB ID: CDBP00413474
- Locus: chr21-15326060-15327391
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Data sourse: GSE67783, GSE86191, GSE116868, GSE111913, GSE206145
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Cell type: RPE, HCT-116, MB157, RT-112, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 67%,
"9_Het": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, POU2F2, CHD8, SMC1A, TBL1X, MYCN, POU5F1, FOXA2, KDM4C, ZFX, POU4F2, XBP1, RUNX1T1, ZBTB48, WT1, TET2, CDK9, ERG, YY1, RELA, OGG1, ATF3, MYC, SP140, GRHL3, CBFB, ZNF48, MECOM, STAT3, PRDM14, DNMT3B, NR3C1, NCOA3, ELF1, CEBPD, TRIM28, TFAP2C, NR2F1, ZNF680, ESR1, OCA2, GRHL2, CTCF, JUN, ARRB1, SPI1, AR, GATA6, IKZF5, RXR, TRIM24, MXD3, HEXIM1, EGR1, FLI1, HSF1, ZBTB26, NOTCH3, BRD4, IRF4, MAZ, AATF, SMC3, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops