- Basic information
- CohesinDB ID: CDBP00413477
- Locus: chr21-15333888-15335484
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Data sourse: GSE67783, GSE86191, GSE98367, GSE206145-NatGen2015, ENCSR153HNT, GSE103477, GSE111537
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Cell type: Fibroblast, HCT-116, THP-1, K-562, OCI-AML-3, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 88%,
"7_Enh": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, SMC1A, CHD8, CEBPA, ZNF263, POU5F1, SOX2, ZFX, STAT1, MEF2C, CDK9, ERG, RELA, RUNX2, CDK6, SMARCA4, RAD21, BHLHE22, ZNF48, NFE2, MED1, VDR, JMJD1C, CEBPB, TRIM28, MYB, MYOD1, STAT5A, CTCF, SPI1, BCL11A, NOTCH3, BRD4, SMC3, MLLT1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops