- Basic information
- CohesinDB ID: CDBP00413498
- Locus: chr21-15422712-15423238
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Data sourse: GSE105004, GSE138405, GSE101921, GSE85526, GSE206145-NatGen2015, GSE68388, GSE116344, GSE126990
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Cell type: HMEC, Hela-Kyoto, Fibroblast, RH4, HEKn, HeLa, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 60%,
"7_Enh": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, SOX2, FOXA1, MLL4, ATF3, NFIC, CHD7, RUNX3, MORC2, CBFB, TP63, MAF, TEAD1, TRIM28, ZNF573, ETV1, NFE2L2, ESR1, TP73, CTCF, JUN, EP300, TEAD4, TFAP2C, EED, CHD8, MTA2, DUX4, STAT1, ERG, HOXC5, MYC, ARID1B, RXRA, NKX2-1, STAT3, NKX3-1, IKZF1, RCOR1, ARNTL, VDR, NR3C1, GRHL2, SPI1, GATA2, FLI1, RELB, MRTFB, SMC1A, NKX2-2, AFF4, ZFX, SMAD3, RUNX2, PBX4, DAXX, ATF2, HMBOX1, FOXM1, FOS, MED1, MYB, RBM22, SP1, BCL11A, SMAD2-3, SMC3, MLLT1, STAG2, FOXA2, MTA3, CDK9, KDM1A, YY1, RELA, TARDBP, JUNB, HIF1A, BATF, MAX, TP53, NFKB1, MYOD1, TBX21, PAX3-FOXO1, AR, YAP1, IKZF2, BRD4, JUND, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops