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Basic information

CohesinDB ID: CDBP00413506

Locus: chr21-15446197-15446869

Data sourse: ENCSR000BLD, GSE98367, ENCSR000ECE, GSE83726, GSE138105, GSE116344

Cell type: H1-hESC, SLK, RH4, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 72%, "7_Enh": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, PGR, HMG20A, SOX2, MEIS2, HNF1A, XBP1, SNAPC4, FOXA1, RBFOX2, RXRB, PBX2, KDM3A, TFAP4, TSC22D4, THRB, NFIC, ATF3, ZFP64, HNRNPUL1, CHD7, WDHD1, PRDM1, RUNX3, MXD4, MECOM, PAX5, BACH2, TEAD1, ELF1, TRIM28, KLF6, BCLAF1, NFE2L2, KLF10, RCOR2, ESR1, ZNF217, MED26, OCA2, MLL, LMO2, CTCF, TCF12, EP300, BAF155, SOX5, DPF2, SIX5, IRF4, SOX6, E2F1, RFX3, TEAD4, FOXA3, ZNF175, GATAD2A, GTF2F1, RBPJ, MLX, TFAP2C, EED, NANOG, CHD8, POU2F2, POU5F1, BRD3, HHEX, ID3, ZNF263, CTBP1, MTA2, RUNX1T1, STAT1, NONO, SRF, GATAD1, SAP130, ARID3A, TBP, HNF4G, ERG, SMARCC2, ETS1, MYC, EZH1, HOMEZ, RAD21, GRHL3, RXRA, GABPA, MCRS1, STAT3, ZNF614, UBN1, XRCC5, NKX3-1, IKZF1, NFE2, MIER3, NR2F6, VDR, ARNTL, NR3C1, CEBPB, ESRRA, KMT2A, CREB1, CCAR2, TBL1XR1, EZH2, GRHL2, ZNF652, TRPS1, GABPB1, ZHX2, SPI1, TFE3, MIXL1, HBP1, HDAC2, GATA2, SSRP1, ZNF644, INTS13, MXD3, SIX2, FLI1, DRAP1, ZGPAT, MXI1, RELB, NFIL3, MRTFB, NCOA2, ETV5, RUNX1, THAP11, BCL6, SMC1A, CEBPA, MAFG, CBX1, SOX13, AFF4, SIN3A, ZFX, SMAD3, TBX3, SP5, TRIM22, SMARCC1, MEF2A, MYBL2, RARA, ZNF384, ZXDC, CREBBP, NFYC, RUNX2, CDK6, GATA4, NRF1, BACH1, ARNT, NFIB, ZNF48, ATF2, SMAD4, PBX3, FOXM1, ETV6, FOS, HMGXB4, CDK8, TGIF2, CHD1, MED1, TEAD3, ZEB1, CEBPD, PIAS1, ZMYM3, SMAD1, ZNF3, KLF9, C11orf30, EVI1, MBD1, STAT5A, RBM22, MAFK, BCL11A, SP1, NIPBL, HNF4A, NR4A1, GSPT2, USF1, TFAP2A, IKZF5, REST, ZBTB7A, ATF7, ASH2L, CTBP2, MBD2, FOXP1, BCOR, TCF3, SMC3, ELL2, STAG1, MLLT1, ETV4, NFATC3, SKI, ZNF283, MEF2B, PPARG, FOXA2, ZNF316, CREM, MEIS1, RBBP5, MTA3, MIER2, CHD2, GTF2B, MAFF, ZBTB33, TCF7, MEF2C, CDK9, ZNF580, HOXB13, BCL3, KDM1A, YY1, FOXO3, RELA, ZKSCAN1, TARDBP, JUNB, AHR, HIF1A, GATA3, ZNF519, BATF, TAL1, MAX, NRIP1, ZNF143, AGO2, SPIB, CEBPG, NCOA3, NR2F2, TCF7L2, NR2F1, PKNOX1, ZNF334, MYOD1, PHF5A, BRD2, KAT8, ELF3, TBX21, ARID4B, AR, NFKBIZ, PAX3-FOXO1, BHLHE40, TAF1, RXR, EGLN2, ZBTB26, IKZF2, BRD4, JUND, MAZ, SMAD4.1D12, ZNF24, DMAP1, FOSL2

Target gene symbol (double-evidenced CRMs): NRIP1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000180530,

eachgene

Deatailed information for cohesin site CDBP00413506