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Basic information

CohesinDB ID: CDBP00413507

Locus: chr21-15448526-15449052

Data sourse: ENCSR000BLD, ENCSR000BTQ, GSE206145-GSE177045, GSE72082, ENCSR703TNG, GSE76893, ENCSR000EDE, GSE116344, GSE25021

Cell type: MCF-7, H1-hESC, HeLa-S3, RH4

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 78%, "9_Het": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: TRIM28, RAD21, DUX4, CTCF, ZNF143, STAG1

Target gene symbol (double-evidenced CRMs): NRIP1

Function elements

Human SNPs: Chronic_inflammatory_diseases_(ankylosing_spondylitis,_Crohn's_disease,_psoriasis,_primary_sclerosing_cholangitis,_ulcerative_colitis)_(pleiotropy)

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000180530,

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Deatailed information for cohesin site CDBP00413507