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Basic information

CohesinDB ID: CDBP00413508

Locus: chr21-15455633-15456680

Data sourse: ENCSR167MTG, ENCSR000EEG, ENCSR338DUC, ENCSR230ZWH, GSE67783, GSE72082, GSE86191, GSE111913, GSE76893, ENCSR000BLS, GSE206145, GSE206145-NatGen2015, ENCSR054FKH, ENCSR153HNT, GSE25021, ENCSR000EDW, ENCSR917QNE

Cell type: RPE, Fibroblast, HCT-116, Hep-G2, RT-112, K-562, Liver, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 6% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.911

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 74%, "7_Enh": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, HMG20A, FOXA1, RBFOX2, RXRB, KDM3A, TFAP4, TSC22D4, ATF3, NFIC, ZFP64, MXD4, CDX2, TEAD1, RBM39, KLF6, KLF10, RCOR2, ESR1, OCA2, CTCF, BAF155, EP300, SOX5, DPF2, RFX5, TEAD4, FOXA3, ZNF175, GATAD2A, RBPJ, MLX, NANOG, CHD8, ZSCAN5D, MYCN, DUX4, ZSCAN5A, ZBTB48, GATAD1, SAP130, ARID3A, HNF4G, ERG, ETS1, MYC, HOMEZ, RAD21, RXRA, FOXK2, MCRS1, XRCC5, ZNF614, NKX3-1, IKZF1, MIER3, NR2F6, CEBPB, HNRNPL, CREB1, TBL1XR1, ZNF652, GABPB1, ZHX2, TFE3, MIXL1, HDAC2, GATA2, ZNF644, MXD3, DRAP1, ZGPAT, NFIL3, ETV5, PTBP1, RUNX1, THAP11, BCL6, SMC1A, CEBPA, CBX1, SOX13, ZFX, TET2, SP5, SMARCC1, RARA, GATA4, ARNT, ZNF48, SMAD4, HMGXB4, MED1, TEAD3, CEBPD, PIAS1, ZMYM3, RBM22, MAFK, SP1, HNF4A, IKZF5, REST, ASH2L, FOXP1, SMC3, STAG1, SKI, PPARG, FOXA2, TBL1X, CREM, MIER2, WT1, TCF7, HOXB13, ZNF580, KDM1A, YY1, RELA, AHR, SP140, MAX, TLE3, CEBPG, NR2F2, ELF3, PHF5A, KAT8, NFKBIZ, AR, ARID4B, ZBTB26, HSF1, NOTCH3, BRD4, JUND, CUX1, MAZ, DMAP1, FOSL2

Target gene symbol (double-evidenced CRMs): NRIP1,RBM11

Function elements

Human SNPs: Lymphocyte_counts

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000185272, ENSG00000180530,

eachgene

Deatailed information for cohesin site CDBP00413508