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Basic information

CohesinDB ID: CDBP00413514

Locus: chr21-15495910-15496512

Data sourse: ENCSR000BLD, GSE97394, ENCSR167MTG, ENCSR000EEG, GSE72082, GSE138405, GSE25021, ENCSR000BLS, GSE105028, GSE85526, ENCSR000ECE, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE116344, GSE126990, GSE145327, ENCSR000ECS

Cell type: MCF-7, H1-hESC, Hela-Kyoto, RH4, HEKn, Hep-G2, HeLa-S3, HUES64, K-562, HuCC-T1, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 7% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.878

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 83%, "7_Enh": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, POU2F2, CHD8, SMC1A, PGR, POU5F1, MYCN, CEBPA, ZFX, TEAD4, SMAD3, STAT1, FOXA1, SRF, CDK9, TWIST1, HNF4G, HOXC5, RELA, JUNB, ETS1, RUNX2, ATF3, MYC, HOMEZ, RAD21, ISL1, GRHL3, PBX4, DAXX, GR, NKX2-1, GATA3, RXRA, TAL1, MAX, STAT3, XRCC5, FOS, GATA1, HAND2, MED1, ARNTL, KLF4, CEBPB, NR3C1, TEAD3, TEAD1, KMT2A, CREB1, EBF3, PHOX2B, JUN, ZHX2, CTCF, SPI1, EP300, AR, GATA2, FLI1, ZBTB26, BRD4, JUND, SMC3, TBX2, STAG1, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): HSPA13,RBM11,NRIP1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000185272, ENSG00000155304, ENSG00000180530,

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Deatailed information for cohesin site CDBP00413514