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Basic information

CohesinDB ID: CDBP00413528

Locus: chr21-15574421-15574823

Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, ENCSR000BLY, GSE105028, GSE25021, ENCSR000EFJ, ENCSR000BTU, GSE138405, GSE101921, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, ENCSR000BLS, GSE206145, ENCSR000ECE, GSE97394, ENCSR000BTQ, ENCSR167MTG, ENCSR000EDE, GSE126990, ENCSR000ECS

Cell type: MCF-7, H1-hESC, HMEC, Fibroblast, Hela-Kyoto, RPE, Hep-G2, SLK, Ishikawa, HCAEC, HeLa-S3, HUES64, IMR-90, SK-N-SH, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 8% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.833

Subunit: SMC3,Rad21,SA2,SA1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 56% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 94%, "14_ReprPCWk": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: GATA1, TEAD1, RAD21, STAG2, ARNT, ESR1, FOXA1, SMC3, CTCF, HOXB13, STAG1

Target gene symbol (double-evidenced CRMs): NRIP1,SAMSN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000155307, ENSG00000180530,

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Deatailed information for cohesin site CDBP00413528