- Basic information
- CohesinDB ID: CDBP00413544
- Locus: chr21-15631324-15631811
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Data sourse: GSE206145-GSE177045, GSE138405, GSE206145, GSE206145-NatGen2015, ENCSR000EDE, GSE126990, GSE108869
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Cell type: MCF-7, RPE, Hela-Kyoto, Fibroblast, HeLa-S3
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
56% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 91%,
"7_Enh": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, SMC1A, FOXA2, MAFF, FOXA1, HOXB13, SMARCC1, ERG, HOXC5, RELA, JUNB, ATF3, RFX1, RAD21, PBX4, MAFB, FOS, MED1, CEBPB, PIAS1, NFKB1, JUN, CTCF, MAFK, SPI1, BAF155, EP300, BHLHE40, AR, GATA2, FLI1, JUND, BRD4, CLOCK, MRTFB, ZNF175, FOSL2
- Target gene symbol (double-evidenced CRMs): USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops