- Basic information
- CohesinDB ID: CDBP00413546
- Locus: chr21-15639024-15639642
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Data sourse: ENCSR000BTU, ENCSR167MTG, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE138405, GSE25021, GSE206145, ENCSR000EDE, GSE68388, ENCSR703TNG, GSE126990, ENCSR000ECS, ENCSR917QNE
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Cell type: MCF-7, RPE, Hela-Kyoto, Hep-G2, Ishikawa, HeLa-S3, Liver, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
56% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 80%,
"7_Enh": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, PGR, HMG20A, SOX2, FOXA1, HLF, KDM3A, TFAP4, NFIC, TP63, SFPQ, CDX2, TEAD1, ELF1, ETV1, ZNF217, ESR1, JUN, CTCF, EP300, BAF155, SOX5, GATA6, E2F6, IRF4, PRKDC, TEAD4, FOXA3, GATAD2A, TFAP2C, NANOG, CHD8, SAP130, ERG, MYC, SMARCA4, EOMES, HOMEZ, RAD21, RXRA, GABPA, STAT3, UBN1, NKX3-1, MIER3, NR2F6, VDR, NR3C1, CEBPB, CREB1, GRHL2, TRPS1, SPI1, MIXL1, TFE3, GATA2, ZNF644, ZGPAT, NFIL3, THAP11, SMC1A, BCL6, CEBPA, NKX2-2, SOX13, SIN3A, POU4F2, SMARCC1, RARA, CREBBP, RUNX2, GATA4, GR, ARNT, PBX4, SMAD4, FOS, TEAD3, CEBPD, SCRT2, PIAS1, TBX5, SP1, HNF4A, IKZF5, ASH2L, FOXP1, SMC3, FOXA2, MIER2, KDM1A, YY1, RELA, JUNB, HIF1A, GATA3, MAX, CEBPG, KLF4, TCF7L2, NFKB1, MYOD1, AR, YAP1, EGLN2, JUND, BRD4, SCRT1, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops