- Basic information
- CohesinDB ID: CDBP00413559
- Locus: chr21-15686198-15689798
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Data sourse: GSE67783, GSE98367, GSE138405, GSE206145, GSE206145-NatGen2015, GSE55407, GSE120943, GSE126990, GSE50893, GSE126755, GSE165895
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Cell type: RPE, GM18526, Fibroblast, Hela-Kyoto, Monocytes, THP-1, Neutrophil, HSPC, Macrophage, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES,Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
56% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 61%,
"7_Enh": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, SKI, ZNF283, SMC1A, TOP2A, STAT1, FOXA1, MLLT3, MEF2C, SUZ12, CDK9, KDM1A, RELA, CDK6, RAD21, ZNF143, CDK8, JMJD1C, TRIM28, KMT2A, MLL, EVI1, SPI1, NR4A1, IRF1, TRIM24, BRD4, MLLT1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 23
- Related genes and loops