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Basic information

CohesinDB ID: CDBP00413568

Locus: chr21-15722383-15723272

Data sourse: ENCSR000BLD, ENCSR000BTQ, ENCSR000BTU, GSE206145-GSE177045, GSE72082, GSE76893, ENCSR000ECE, GSE68388, ENCSR703TNG, GSE25021, GSE115602

Cell type: MCF-7, H1-hESC, Ishikawa, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 6% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,SA1,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 56% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 76%, "9_Het": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, SOX2, NME2, FOXA1, RXRB, NFIC, CHD7, WDHD1, SMARCE1, TEAD1, TRIM28, ZNF217, ESR1, TCF12, BAF155, EP300, DPF2, E2F4, E2F1, TEAD4, TFAP2C, NANOG, TOP2A, CTBP1, SRF, ERG, RAD21, NKX2-1, STAT3, NKX3-1, VDR, NR3C1, ESRRA, CEBPB, CREB1, GRHL2, ZNF652, SPI1, HDAC2, GATA2, CBX1, SMC1A, SIN3A, SMAD3, ZXDC, CREBBP, PBX4, ARNT, FOXM1, CDK8, PIAS1, USF1, SP1, BCL11A, NIPBL, ZBTB7A, ASH2L, CTBP2, MBD2, FOXP1, STAG1, PPARG, FOXA2, RBBP5, HOXB13, YY1, RELA, MCM3, TCF4, HIF1A, GATA3, MAX, NRIP1, ZNF143, GATA1, TLE3, KLF4, NR2F2, TCF7L2, KDM5B, ZNF687, AR, ZNF579, EGLN2, EGR1, BRD4, CUX1, AHR

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00413568