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Basic information

CohesinDB ID: CDBP00413577

Locus: chr21-15752991-15753477

Data sourse: ENCSR000BLD, GSE105028, ENCSR000ECE, GSE97394, GSE64758

Cell type: H1-hESC, HUES64, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: NIPBL,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 58% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "7_Enh": 46%, "5_TxWk": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, HMG20A, SOX2, MEIS2, HNF1A, PATZ1, FOXA1, PBX2, RXRB, HNRNPK, HDGF, ATF3, NFIC, CHD7, PRDM1, ATF4, SMARCE1, MITF, BACH2, ZNF467, ZNF629, TEAD1, TRIM28, KLF6, SNAI2, NFE2L2, SAP30, RCOR2, HNF1B, USF2, JUN, TCF12, EP300, E4F1, MNT, SOX5, DPF2, E2F6, TRIM24, E2F4, RAD51, TEAD4, FOXA3, ZNF175, GATAD2A, PDX1, TFAP2C, GLIS1, NANOG, CHD8, POU5F1, SAP130, NBN, HIC1, SP4, ARID3A, ERG, MYC, SMARCA4, EOMES, ARID1B, RAD21, HOMEZ, GRHL3, RXRA, NKX2-1, FOXK2, STAT3, ZNF614, PRDM14, IKZF1, NFE2, NR2F6, VDR, NR3C1, CEBPB, KMT2A, CREB1, EZH2, GRHL2, EBF3, ZHX2, SPI1, MIXL1, IRF1, HDAC2, ZNF644, DRAP1, ZGPAT, ZNF766, NFIL3, THAP11, MAFG, BCL6, CEBPA, SMC1A, SIN3A, SOX13, SMAD3, MYBL2, RARA, NOTCH1, BRD9, RUNX2, SMAD2, CDK6, OSR2, ZNF184, PBX4, BACH1, ATF2, HMGB2, ZEB2, CBFA2T3, MAFB, FOS, CHD1, MED1, TEAD3, SPDEF, ZEB1, C11orf30, L3MBTL2, SETDB1, RBM22, USF1, SP1, TFAP2A, NIPBL, BCL11A, MAFK, IKZF5, REST, ZNF479, ZBTB7A, ASH2L, PHIP, FOXP1, PRDM6, CBFA2T2, PPARG, CBX3, FOXA2, EBF1, GTF2B, WT1, MAFF, KDM1A, YY1, RELA, NEUROD1, JUNB, ZIC2, HIF1A, OTX2, GATA3, TAL1, MAX, ZNF143, GATA1, KLF4, NR2F1, TP53, PKNOX1, NFKB1, T, BRD2, ELF3, KAT8, BHLHE40, AR, ARID4B, TAF1, NFKBIZ, ZNF366, ZBTB42, RNF2, JUND, BRD4, MAZ, ZNF24, ZNF316, FOSL2

Target gene symbol (double-evidenced CRMs): USP25

Function elements

Human SNPs: .

Number of somatic mutations (coding): 12

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000155313,

eachgene

Deatailed information for cohesin site CDBP00413577