Deatailed information for cohesin site CDBP00413578
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- Basic information
- CohesinDB ID: CDBP00413578
- Locus: chr21-15754315-15755248
- Data sourse: ENCSR895JMI, ENCSR853VWZ, ENCSR956LGB, GSE72082, ENCSR193NSH, ENCSR501LQA, ENCSR150EFU, GSE138105, ENCSR054FKH, ENCSR247LSH, ENCSR981FDC, ENCSR620NWG, GSE85526, ENCSR767DFK, GSE206145-NatGen2015, GSE206145, ENCSR984DZW, ENCSR000BUC, GSE165895
- Cell type: RPE, Fibroblast, Hep-G2, HEKn, SLK, A-549, HFFc6
- DNA Sequence of binding site: UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: Mau2,SMC3,Rad21,SMC1
- CTCF binding site: non-CTCF CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
- Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
- Compartment: 58% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"7_Enh": 47%,
"5_TxWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2). - Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, HMG20A, SOX2, MEIS2, HNF1A, PATZ1, FOXA1, PBX2, RXRB, HNRNPK, HDGF, ATF3, NFIC, CHD7, PRDM1, ATF4, SMARCE1, MITF, BACH2, ZNF467, ZNF629, TEAD1, TRIM28, KLF6, SNAI2, NFE2L2, SAP30, RCOR2, HNF1B, USF2, JUN, TCF12, EP300, E4F1, MNT, SOX5, DPF2, E2F6, TRIM24, E2F4, RAD51, TEAD4, FOXA3, ZNF175, GATAD2A, PDX1, TFAP2C, GLIS1, NANOG, CHD8, POU5F1, SAP130, NBN, HIC1, SP4, ARID3A, ERG, MYC, SMARCA4, EOMES, ARID1B, RAD21, HOMEZ, GRHL3, RXRA, NKX2-1, FOXK2, STAT3, ZNF614, PRDM14, IKZF1, NFE2, NR2F6, VDR, NR3C1, CEBPB, KMT2A, CREB1, EZH2, GRHL2, EBF3, ZHX2, SPI1, MIXL1, IRF1, HDAC2, ZNF644, DRAP1, ZGPAT, ZNF766, NFIL3, THAP11, MAFG, BCL6, CEBPA, SMC1A, SIN3A, SOX13, SMAD3, MYBL2, RARA, NOTCH1, BRD9, RUNX2, SMAD2, CDK6, OSR2, ZNF184, PBX4, BACH1, ATF2, HMGB2, ZEB2, CBFA2T3, MAFB, FOS, CHD1, MED1, TEAD3, SPDEF, ZEB1, C11orf30, L3MBTL2, SETDB1, RBM22, USF1, SP1, TFAP2A, NIPBL, BCL11A, MAFK, IKZF5, REST, ZNF479, ZBTB7A, ASH2L, PHIP, FOXP1, PRDM6, CBFA2T2, PPARG, CBX3, FOXA2, EBF1, GTF2B, WT1, MAFF, KDM1A, YY1, RELA, NEUROD1, JUNB, ZIC2, HIF1A, OTX2, GATA3, TAL1, MAX, ZNF143, GATA1, KLF4, NR2F1, TP53, PKNOX1, NFKB1, T, BRD2, ELF3, KAT8, BHLHE40, AR, ARID4B, TAF1, NFKBIZ, ZNF366, ZBTB42, RNF2, JUND, BRD4, MAZ, ZNF24, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): USP25
- Function elements
- Human SNPs: QRS_complex_(12-leadsum)
- Number of somatic mutations (coding): 32
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene: ENSG00000155313,
- Related loop: chr21:14075000-14100000~~chr21:15725000-15750000, chr21:14375000-14400000~~chr21:15725000-15750000, chr21:14875000-14900000~~chr21:15725000-15750000, chr21:14975000-15000000~~chr21:15725000-15750000, chr21:15625000-15650000~~chr21:15725000-15750000, chr21:15725000-15750000~~chr21:15825000-15850000, chr21:15725000-15750000~~chr21:16400000-16425000, chr21:15725000-15750000~~chr21:17600000-17625000, chr21:15725000-15750000~~chr21:17775000-17800000, chr21:15750000-15775000~~chr21:15850000-15875000, chr21:15750000-15775000~~chr21:16175000-16200000, chr21:15750000-15775000~~chr21:17050000-17075000,
Tools:
- Assay
