- Basic information
- CohesinDB ID: CDBP00413582
- Locus: chr21-15768157-15768884
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Data sourse: GSE138405, GSE62063
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Cell type: Hela-Kyoto, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
58% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 65%,
"15_Quies": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, PGR, HMG20A, SOX2, FOXA1, RXRB, PBX2, MEN1, ZNF362, ZBTB44, PRDM1, ZNF189, TP63, CDX2, ZNF629, TEAD1, SNAI2, KLF10, SAP30, ESR1, CTCF, JUN, EP300, BAF155, SOX5, PRDM4, FOXA3, GATAD2A, TOP2A, ZNF317, ZBTB48, ZNF205, SRF, GATAD1, SAP130, ARID3A, HIC1, HNF4G, ERG, ZNF341, TSHZ1, HOMEZ, RAD21, ZNF614, NKX3-1, RCOR1, NR2F6, NR3C1, CEBPB, CREB1, KLF8, FEZF1, MIXL1, IRF1, GATA2, ZNF644, FLI1, DRAP1, ZGPAT, HEXIM1-CDK9, NFIL3, MRTFB, BCL6, MAFG, SOX13, RARA, ZNF384, RUNX2, OSR2, GR, PBX4, ARNT, SMAD4, ZEB2, ZNF10, SUPT5H, MED1, TEAD3, CEBPD, PIAS1, ZNF879, C11orf30, RBM22, NUP98-HOXA9, BCL11A, MAFK, ARID1A, PHIP, FOXP1, PRDM6, ZNF34, PPARG, FOXA2, WT1, MAFF, HOXB13, KDM1A, RELA, BRG1, HIF1A, GATA3, MAX, GATA1, TLE3, BCL11B, TP53, PKNOX1, ELF3, ZNF843, ARID4B, AR, YAP1, BRD4, JUND, BRCA1, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 32
- Number of somatic mutations (non-coding): 7
- Related genes and loops