- Basic information
- CohesinDB ID: CDBP00413583
- Locus: chr21-15774442-15775435
-
Data sourse: GSE206145, GSE206145-NatGen2015
-
Cell type: RPE, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1,Rad21,SA2
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
58% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"5_TxWk": 61%,
"7_Enh": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: PGR, FOXA2, ZNF496, TOP2A, MEIS2, SMAD3, FOXA1, HLF, HOXC5, RELA, NEUROD1, JUNB, ATF3, PBX4, OTX2, GATA3, STAT3, PBX3, FOS, MED1, NR3C1, CEBPB, CEBPD, ZFP91, JUN, MAFK, BHLHE40, IRF1, GATA2, BRD4, NFIL3, FOSL2
- Target gene symbol (double-evidenced CRMs): USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops