- Basic information
- CohesinDB ID: CDBP00413584
- Locus: chr21-15775679-15776594
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Data sourse: ENCSR000EFJ, GSE138405, ShirahigeLab, ShirahigeLab-NatGen2015, GSE165895
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Cell type: RPE, Hela-Kyoto, Fibroblast, IMR-90, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
58% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 65%,
"7_Enh": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, PGR, CHD8, SMARCA2, EZH2phosphoT487, TOP2A, POU4F2, GTF2B, SMAD3, FOXF1, ZBTB33, MEF2C, HOXB13, HOXC5, RELA, JUNB, RUNX2, CHD7, PRDM1, PBX4, DAXX, RAD21, OTX2, STAT3, TP63, FOS, CDK8, RCOR1, MED1, ARNTL, NR3C1, CEBPB, JMJD1C, ELF1, TRIM28, NR2F2, ESR1, TP73, MYOD1, ELF3, BRD2, RBM22, SPI1, JUN, TCF12, BCL11A, AR, GATA2, FLI1, BRD4, PHIP, MRTFB, FOSL2
- Target gene symbol (double-evidenced CRMs): USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 44
- Number of somatic mutations (non-coding): 0
- Related genes and loops