- Basic information
- CohesinDB ID: CDBP00413586
- Locus: chr21-15781953-15782661
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Data sourse: GSE67783, GSE111913, ENCSR153HNT, GSE86191
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Cell type: K-562, RT-112, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
58% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 62%,
"8_ZNF/Rpts": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBX5, XBP1, FOXA1, LEO1, MORC2, CBFB, PAX5, TP63, ELF1, TRIM28, LMO2, ESR1, OCA2, MED26, TP73, CTCF, E2F1, EED, POU2F2, CHD8, BRD1, ZSCAN5D, ZNF263, POU5F1, MYCN, KDM4C, TOP2A, ZBTB48, MYC, EZH1, SMARCA4, GRHL3, STAT3, IKZF1, DNMT3B, ARNTL, NR3C1, CEBPB, KMT2A, EZH2, GRHL2, SPI1, IRF1, GATA2, ZNF490, RUNX1, SMC1A, CRY1, ZFX, POU4F2, TET2, CREBBP, RUNX2, NRF1, ATF2, SUPT5H, CDK8, MYB, SETDB1, RBM22, GSPT2, FOXP1, SMC3, STAG1, TBL1X, FOXA2, PAF1, GTF2B, WT1, ZBTB33, CDK9, HOXB13, MPHOSPH8, RELA, NEUROD1, SP140, HIF1A, MAX, AGO2, NCOA3, ZNF791, PHOX2B, AR, HSF1, ZBTB26, NOTCH3, BRD4, MAZ, BRCA1, AHR
- Target gene symbol (double-evidenced CRMs): USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops