- Basic information
- CohesinDB ID: CDBP00413588
- Locus: chr21-15788870-15789636
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE138405, GSE206145, GSE101921, GSE85526, GSE206145-NatGen2015, ENCSR767DFK, ENCSR703TNG, GSE126990, GSE108869, ENCSR000ECS
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Cell type: MCF-7, RPE, Fibroblast, Hela-Kyoto, HEKn, A-549, HCAEC, HeLa-S3
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
58% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 55%,
"15_Quies": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, FOXA1, MEN1, NFIC, CHD7, PRDM1, TEAD1, TRIM28, ETV1, ZNF217, ESR1, JUN, TCF12, EP300, GATA6, DPF2, SMC1, TEAD4, ZNF92, CHD8, CTBP1, STAT1, SRF, ERG, MYC, RAD21, LHX2, NKX2-1, GABPA, STAT3, NKX3-1, NR3C1, CEBPB, GRHL2, TRPS1, MRTFA, SPI1, EHF, IRF1, GATA2, FLI1, MRTFB, SMC1A, SIN3A, ZNF534, SMAD3, SMARCC1, CREBBP, RUNX2, GATA4, GR, PBX4, ARNT, PRDM9, PBX3, FOS, SUPT5H, MED1, PIAS1, C11orf30, ZHX1, HOXA9, CTBP2, SMC3, PPARG, FOXA2, PAF1, FOXF1, RELA, NEUROD1, JUNB, AHR, HIF1A, OTX2, GATA3, TAL1, MAX, GATA1, TP53, PKNOX1, ELF3, AR, YAP1, HSF1, BRD4, JUND, ZNF316
- Target gene symbol (double-evidenced CRMs): USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 20
- Number of somatic mutations (non-coding): 0
- Related genes and loops