- Basic information
- CohesinDB ID: CDBP00413599
- Locus: chr21-15827702-15827852
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
58% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 61%,
"4_Tx": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF660, SOX2, NME2, FOXA1, HLF, RXRB, KDM3A, ATF3, CTCFL, PRDM1, ATF4, ZSCAN4, JMJD1C, THRAP3, TEAD1, BCLAF1, TRIM28, ETV1, KLF6, ELF1, RCOR2, ZNF217, ESR1, CTCF, JUN, EP300, GATA6, SOX5, PRDM4, IRF4, TRIM24, DEK, RAD51, SMC1, TEAD4, FOXA3, GATAD2A, PDX1, POU2F2, POU5F1, ZNF317, STAT1, SRF, GATAD1, SAP130, DDX5, ARID3A, HOXC5, ERG, MYC, EZH1, SMARCA4, HOMEZ, RAD21, ARID1B, RXRA, NKX2-1, PROX1, GABPA, STAT3, ZNF614, NKX3-1, MIER3, NFE2, NR2F6, RCOR1, NR3C1, CEBPB, CREB1, EZH2, GRHL2, ZNF652, ZHX2, SPI1, MIXL1, HDAC2, GATA2, ZNF644, FLI1, ZGPAT, ZNF766, NFIL3, MRTFB, RUNX1, THAP11, SMC1A, BCL6, CBX1, CEBPA, NKX2-2, SOX13, AFF4, SMAD3, ZNF654, TRIM22, ZBTB2, RARA, ZNF35, GATA4, PBX4, ARNT, ATF2, ZNF48, SMAD4, ZEB2, FOS, HMGXB4, CDK8, SUPT5H, MED1, TEAD3, MYB, SCRT2, PIAS1, SMAD1, C11orf30, TBX5, MBD1, NUP98-HOXA9, RBM22, SP1, BCL11A, MAFK, HNF4A, REST, ZHX1, ASH2L, FOXP1, SMC3, STAG2, STAG1, PAX7, SKI, PPARG, FOXA2, CREM, PAF1, MIER2, GTF2B, WT1, MAFF, CDK9, HOXB13, KDM1A, YY1, RELA, NEUROD1, CHAMP1, HIF1A, OTX2, GATA3, BATF, MAX, ZNF143, CEBPG, NEUROG2, KDM5B, TP53, PKNOX1, ELF3, KAT8, TBX21, ARID4B, AR, NOTCH3, SCRT1, ILF3, BRD4, JUND, ZNF24, ZNF316
- Target gene symbol (double-evidenced CRMs): NRIP1,HSPA13,USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000155304,
ENSG00000180530,
ENSG00000155313,
- Related loop:
chr21:14250000-14275000~~chr21:15825000-15850000,
chr21:14375000-14400000~~chr21:15800000-15825000,
chr21:14375000-14400000~~chr21:15825000-15850000,
chr21:15050000-15075000~~chr21:15825000-15850000,
chr21:15500000-15525000~~chr21:15825000-15850000,
chr21:15520229-15521680~~chr21:15825383-15827192,
chr21:15520337-15521600~~chr21:15825285-15827222,
chr21:15520438-15521729~~chr21:15825379-15827213,
chr21:15575000-15600000~~chr21:15800000-15825000,
chr21:15591163-15593391~~chr21:15825411-15827711,
chr21:15591857-15593440~~chr21:15825433-15827080,
chr21:15600000-15625000~~chr21:15800000-15825000,
chr21:15600000-15625000~~chr21:15825000-15850000,
chr21:15625000-15650000~~chr21:15825000-15850000,
chr21:15678908-15680651~~chr21:15825379-15827213,
chr21:15678925-15680577~~chr21:15825423-15827778,
chr21:15679142-15680653~~chr21:15824955-15827171,
chr21:15681831-15683975~~chr21:15825446-15827214,
chr21:15725000-15750000~~chr21:15825000-15850000,
chr21:15728981-15731357~~chr21:15825379-15827213,
chr21:15729091-15731386~~chr21:15825686-15827611,
chr21:15729281-15731390~~chr21:15825659-15827066,
chr21:15729455-15730632~~chr21:15825625-15827005,
chr21:15729526-15731390~~chr21:15825285-15827222,