- Basic information
- CohesinDB ID: CDBP00413601
- Locus: chr21-15834852-15835348
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Data sourse: ENCSR000BTU, GSE72082, GSE138405, GSE25021, ENCSR000BLY, GSE206145, GSE101921, ENCSR000EHX, ENCSR703TNG, GSE126990
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Cell type: MCF-7, RPE, Hela-Kyoto, Ishikawa, HCAEC, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
58% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 63%,
"4_Tx": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TOP2A, PAF1, ARNT, GTF2B, BRD4, HIF1A, MAFF, FOXA1, ZNF205, SMC3, CTCF, RBM22, STAG1
- Target gene symbol (double-evidenced CRMs): HSPA13,NRIP1,USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000155304,
ENSG00000180530,
ENSG00000155313,
- Related loop:
chr21:14250000-14275000~~chr21:15825000-15850000,
chr21:14375000-14400000~~chr21:15825000-15850000,
chr21:15050000-15075000~~chr21:15825000-15850000,
chr21:15500000-15525000~~chr21:15825000-15850000,
chr21:15600000-15625000~~chr21:15825000-15850000,
chr21:15625000-15650000~~chr21:15825000-15850000,
chr21:15725000-15750000~~chr21:15825000-15850000,