- Basic information
- CohesinDB ID: CDBP00413602
- Locus: chr21-15837530-15838161
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Data sourse: ShirahigeLab, ShirahigeLab-NatGen2015, GSE138105
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Cell type: RPE, SLK, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
58% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 65%,
"4_Tx": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, BCL6, CHD8, CEBPA, ZNF263, FOXF1, FOXA1, PBX4, GATA3, STAT3, PBX3, CDK8, MED1, CEBPG, CEBPB, NR3C1, CEBPD, ETV1, ESR1, ELF3, TCF12, RBM22, SPI1, AR, GATA2, BRD4, ZNF490
- Target gene symbol (double-evidenced CRMs): HSPA13,USP25,NRIP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000155304,
ENSG00000180530,
ENSG00000155313,
- Related loop:
chr21:14250000-14275000~~chr21:15825000-15850000,
chr21:14375000-14400000~~chr21:15825000-15850000,
chr21:15050000-15075000~~chr21:15825000-15850000,
chr21:15500000-15525000~~chr21:15825000-15850000,
chr21:15600000-15625000~~chr21:15825000-15850000,
chr21:15625000-15650000~~chr21:15825000-15850000,
chr21:15725000-15750000~~chr21:15825000-15850000,