Deatailed information for cohesin site CDBP00413603
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBP00413603
- Locus: chr21-15841385-15842641
- Data sourse: GSE138405, ENCSR000BTU, GSE206145, GSE138105
- Cell type: RPE, SLK, Ishikawa, Hela-Kyoto
- DNA Sequence of binding site: UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,SA1,Rad21,SA2
- CTCF binding site: CTCF CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
- Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
- Compartment: 58% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"5_TxWk": 46%,
"4_Tx": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2). - Co-bound Transcriptional factors: NFIA, FOSL1, CDK6, CHD8, SMARCA2, ZNF496, PPARG, E2F7, TOP2A, PAF1, SOX2, NME2, ZNF316, SMAD3, MAFF, FOXA1, PBX2, HOXB13, SMARCC1, HOXC5, ERG, RELA, YY1, CREBBP, NEUROD1, JUNB, NFIC, RUNX2, EOMES, GATA4, MYC, SMARCA4, LHX2, PBX4, DAXX, NRF1, RXRA, OTX2, GATA3, NKX2-1, SMC3, HIF1A, STAT3, PBX3, FOXM1, TAL1, FOS, SUPT5H, GATA1, MAX, TP63, NUP98-HOXA9, VDR, NR3C1, CEBPB, NR2F2, ELF1, TEAD1, TP53, ESR1, TP73, C11orf30, PHOX2B, JUN, TCF12, RBM22, EP300, ZHX2, SPI1, CTCF, AR, MAFK, TAF1, USF1, GATA2, REST, FLI1, BRD4, JUND, FOXP1, MRTFB, TEAD4, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): HSPA13,USP25,NRIP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 136
- Number of somatic mutations (non-coding): 27
- Related genes and loops
- Related gene: ENSG00000155304, ENSG00000180530, ENSG00000155313,
- Related loop: chr21:14250000-14275000~~chr21:15825000-15850000, chr21:14375000-14400000~~chr21:15825000-15850000, chr21:15050000-15075000~~chr21:15825000-15850000, chr21:15500000-15525000~~chr21:15825000-15850000, chr21:15600000-15625000~~chr21:15825000-15850000, chr21:15625000-15650000~~chr21:15825000-15850000, chr21:15725000-15750000~~chr21:15825000-15850000,
Tools:
- Assay
