- Basic information
- CohesinDB ID: CDBP00413626
- Locus: chr21-15976462-15977602
-
Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR501LQA, GSE126634, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE105028, GSE103477, GSE111537, GSE25021, ENCSR330ELC, GSE108869, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, ENCSR000BKV, GSE115250, GSE138405, GSE76893, GSE101921, GSE135093, GSE152721, GSE206145-NatGen2015, GSE112028, GSE130135, ENCSR199XBQ, ENCSR703TNG, GSE106870, GSE116344, GSE138105, GSE145327, GSE94872, ENCSR895JMI, ENCSR000EEG, ENCSR193NSH, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR807WAC, ENCSR000EHX, ENCSR620NWG, ENCSR748MVX, ENCSR495WGO, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR000BTQ, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, GSE131956, GSE110061, GSE129526, ENCSR676MJK, ENCSR335RKQ, ENCSR000EDE, GSE68388, GSE126990, GSE50893, ENCSR000ECS, GSE131577
-
Cell type: MDM, RH4, GM2610, SLK, CVB-hiPSC, Liver, TC-32, HuCC-T1, H9-hESC, RPE, GM2630, Fibroblast, Ishikawa, GM12890, HeLa-S3, IMR-90, K-562, GM18486, GM18526, H1-hESC, SNYDER, GM12891, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, THP-1, GM19099, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, A-549, HUVEC, HCAEC, GM19238, TC-71, OCI-AML-3, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 32% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.511
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
58% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 98%,
"5_TxWk": 1%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, SMC1A, ZBTB48, FOXA1, SRF, HOXB13, SMARCC1, ERG, HOXC5, RELA, ZBTB2, CTCFL, RAD21, GRHL3, HIF1A, XRCC5, TLE3, ETV1, PIAS1, STAG1, KDM5B, ESR1, CTCF, JUN, BAF155, ZFP28, SPI1, AR, ARID1A, BRD4, SCRT1, HEXIM1-CDK9, SMC1, MRTFB, SMC3, ZNF34, STAG2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops