- Basic information
- CohesinDB ID: CDBP00413632
- Locus: chr21-16001861-16004507
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR501LQA, GSE126634, ENCSR760NPX, ENCSR000BLY, ENCSR404BPV, ENCSR150EFU, GSE105028, GSE103477, GSE111537, GSE131606, ENCSR330ELC, GSE108869, GSE25021, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE165895, ENCSR000EAC, ENCSR000BKV, GSE115250, GSE122299, GSE138405, GSE76893, GSE101921, ENCSR806UKK, GSE135093, GSE152721, ENCSR198ZYJ, GSE206145-NatGen2015, GSE112028, GSE130135, ENCSR199XBQ, ENCSR703TNG, GSE138105, GSE145327, GSE94872, ENCSR895JMI, ENCSR000EEG, ENCSR193NSH, ENCSR768DOX, ENCSR000BLS, ENCSR000EHW, GSE206145, ENCSR000ECE, ENCSR247LSH, ENCSR000BMY, ENCSR000EHX, ENCSR620NWG, ENCSR748MVX, ENCSR767DFK, ENCSR807WAC, ENCSR495WGO, ENCSR981FDC, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR000BTQ, GSE105004, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE131956, GSE110061, ENCSR000HPG, ENCSR676MJK, ENCSR335RKQ, ENCSR054FKH, ENCSR537EFT, ENCSR000EDE, GSE126990, GSE50893, ENCSR000ECS, ENCSR481YWD, GSE131577
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Cell type: MDM, SLK, Liver, TC-32, H9-hESC, RPE, HMEC, Fibroblast, Ishikawa, HeLa-S3, IMR-90, K-562, HFFc6, DKO, H1-hESC, GM12878, GM2588, GBM39, SK-N-SH, HeLa-Tet-On, THP-1, HUES64, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, A-549, HUVEC, HCAEC, HeLa, OCI-AML-3, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 47% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.589
- Subunit: SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
42% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 86%,
"7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, GATA2, FOXA2, TOP2A, NFE2L2, ARNT, HIF1A, FOXA1, GABPA, STAT3, HOXB13, SPI1, ERG
- Target gene symbol (double-evidenced CRMs): USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000155313,
- Related loop:
chr21:15875000-15900000~~chr21:16000000-16025000,
chr21:15975000-16000000~~chr21:16175000-16200000,
chr21:15975000-16000000~~chr21:16325000-16350000,
chr21:15975000-16000000~~chr21:26225000-26250000,
chr21:15975000-16000000~~chr21:28150000-28175000,
chr21:16000000-16025000~~chr21:16175000-16200000,
chr21:16000000-16025000~~chr21:16325000-16350000,
chr21:16000000-16025000~~chr21:16400000-16425000,
chr21:16000000-16025000~~chr21:17250000-17275000,
chr21:16001839-16003762~~chr21:16329724-16331264,
chr21:16001977-16003846~~chr21:16329691-16331745,
chr21:16001998-16003844~~chr21:16329695-16331504,
chr21:16002031-16003807~~chr21:16329708-16331692,
chr21:16002041-16004416~~chr21:16329708-16331761,
chr21:16002066-16003798~~chr21:16329704-16331395,
chr21:16002070-16004771~~chr21:16329660-16331732,
chr21:16002137-16004536~~chr21:16329715-16331630,
chr21:16002506-16003755~~chr21:16329734-16331645,